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This article describes a nondestructive method of determining the drug content of suppositories using near-infrared spectrometry (NIR) combined with chemometrics. The blood supply of the facial skin basically originated from the branches of the facial, superficial temporal and infraorbital arteries. The null mice show severe deficits in short- and long-term object recognition memories, reminiscent of the severe cognitive deficits seen in RTT girls. The fractions contained amino acids (as free amino acids and oligopeptides) in amounts that roughly correlated with their respective conditioning power.

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Blood and bone marrow samples from 24 children with neuroblastoma and 1 child with ganglioneuroma were analyzed. A delay of 5 days was observed between the increase in circulating T4 and T3 concentrations and the enhancement of MDH activity.

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Chemical biology can be defined as the study of biological phenomena from a chemical approach. To evaluate the image quality and acquisition time of magnetic resonance cholangiopancreatography (MRCP) with and without the 3D hybrid profile order technique.

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IRM was composed of zinc oxide interspersed in a matrix of organic material. Diagnosis and physiopathology of neuropathies with acute progress

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Spotlight on AACN: the American Association of Critical Care Nurses. Temporal changes in cerebral tissue oxygenation with cerebrovascular pressure reactivity in severe traumatic brain injury. In the fish Xiphophorus, melanoma can be initiated by simple crossings, and the signaling pathways that govern tumor growth and progression can be delineated. Cerebral microdialysis and P(ti)O2 for neuro-monitoring before decompressive craniectomy.

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This work not only provides relevant constraints that can shape the design of laboratory experiments, it also suggests that sulfide might be a useful proxy for assessing the redox state of sputum in the clinic. Compared to bare metal stents, they significantly reduce restenosis and the need for target vessel revascularization.

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We constructed pairs of eSNPs and SNPs located in the target genes whose expression is regulated by eSNPs. Doxorubicin activity is enhanced by hyperthermia in a model of ex vivo vascular perfusion of human colon carcinoma. In addition, mast cells responded to HBD-1 to -4 with calcium fluxes as well as chemotaxis, which increased upon stimulation with IgE plus antigen or ionomycin. Overall these activities contribute in streamlining efficacy/toxicology evaluation, allowing pharmacologically effective and developable molecules to reach the clinic and eventually to the market. The reasonable accuracy achieved for quantification of the vacuole ion ratios permitted to show (i) that radial gradients of ion ratios in hypocotyls change when the plant is becoming older and (ii) that large differences may exist between adjacent cortical cells of the same type.

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Estrogen-treated OVX rats showed in the morning a lower GABA accumulation in the MPN, MBH and LC, and GABA levels remained unchanged in the LS and MS. Hyaluronate lyases are a class of endoglycosaminidase enzymes, which are of considerable complexity and heterogeneity.

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Molecular cloning and sequencing of the corresponding cDNA indicated that all PfLRRs contain 4-10 LRR motifs. In addition, we provide evidence that variations in VDR level induced by other means (PTH, EGF, medium change) are also closely associated with 1,25-(OH)2D3-induced 24-hydroxylase activity. Similar endothelial lesions were observed in the myocardium, fat bodies, kidneys and spleen.

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The laws do not keep pace with increasing technological risks and are reactive rather than proactive. The results highlight the novel role of BNP as an anti-influenza A viral agent and provide insights into the mechanism of intertypic interference. The data provide a rationale for every second-day administration of intrapulmonary MnSOD-PL in clinical trials of radioprotective gene therapy. Teaching the transrectus sheath preperiotneal mesh repair: TREPP in 9 steps. For comparison purposes between occupationally exposed/non-exposed individuals, a transition was found in the concentration range of 3-10(7) asbestos fibers/g dried lung weight.

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COHRQoL improved with primary dental care for ECC, and there was no statistically significant difference between test and control in the extent of the improvement. Harmful biologic effects of NO in viral respiratory infection might be modified by therapeutic manipulations involving LPA or Rho.

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Maximal mobilization of circulating stem cells was seen five days after Pyran Colopymer injection. Demonstration of numerical equivalence of ensemble and spectral averaging in electromagnetic scattering by random particulate media. The apparent Kd1 of PGE2, however, increased by 10-fold from day 21 of gestation to 1 day postpartum. The bone marrow cellularity and the CFUs content reach a nadir 4 to 6 days after Pyran injection, simultaneous rise in spleen cellularity and CFUs concentration of circulating pluripotent stem cells by a factor of 10 to 45 and a concomitant rise of CFUc is seen.

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Hypertonicity causes water leaving from cells by osmosis, decreasing cell volume and increasing of intracellular ionic strength. Developing an integrated training pathway for clinical academics: notes from the first binational summit meeting.

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Better tactics may be needed, like the targeted screening of children who belong to high-risk groups, to eradicate childhood iron deficiency. Introducing professional educators into academic medicine: stories of exemplars. Frequent consumption of vegetables may reduce the risk of gastric cancer. The system was developed in a cooperative arrangement between an emergency medicine researcher and a medical information software company.

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To evaluate the long-term efficacy of subcutaneous immunotherapy with Dermatophagoides pteronyssinus (DerP) in patients with allergic rhinitis. Using different protein interaction techniques, we studied RoKSN interactions with RoFD and RoFT and possible competition.

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The spectrophotometric signal at 291 nm, produced by the difference in the extinction coefficients between nucleoside substrate and the base product, is significant over a much wider pH range than the signal difference between MESG and its phosphorolysis product at 360 nm. Filopodia formation and Disabled degradation downstream of Reelin.

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BSHX could raise the fertilization rate and promote the early embryonic development. Laryngospasm developed in a 33-year-old woman following attempted endotracheal intubation. Peripheral blood hematopoietic stem cell mobilization and collection efficacy is not an independent prognostic factor for autologous stem cell transplantation. Comparative lipid profile studies in cardiac and diabetic conditions. The role of the oncology clinical nurse specialist: three personal views.

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Of 4318 twin pairs, with no missing values, the placental weights of different gestational ages were analyzed using a nonlinear multivariate Gaussian regression. In addition, both groups developed cross-reactive antibodies and were protected against an intravenous live-virus challenge with SRV-1.

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Phase 1 studies of central memory-derived CD19 CAR T-cell therapy following autologous HSCT in patients with B-cell NHL. Patients with peripheral nodules exhibiting pGGO at the time of the first thin-section CT examination and confirmed histologically by thin-section CT after follow-up of more than 6 months were enrolled in the current study.

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Differential expression within a family of novel wound-induced genes in potato. All seven showed very high levels of LH (25.2-155.0 IU/ml) and FSH (7.1-38.2) upon stimulation with GnRH. The combined use of autologous fibrin membrane and the eye platelet-rich plasma (E-PRP) clot could be considered as a new surgical alternative for the closure of corneal perforations.

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Multivariate analysis (risk state analysis) was performed to evaluate the single and joint effects of pathologic variables on the survivals of 1067 cases of colorectal carcinoma. Biological activity was determined by endothelial cell migration assays. This is partly due to the atypical neurologic symptoms that the patient can present with as a consequence of the size, location, and potential for associated mass effect and oedema. In addition, the potential for melatonin, a potent antioxidant with multiple mitochondrial protective properties, to protect NARP cells exposed to H/RO was assessed.

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We followed a population based cohort of patients with inflammatory bowel disease (IBD) from Olmsted County, Minnesota, in order to analyse long term survival and cause specific mortality. In monolayer cultures of U87 and SKMG-3 cells, rapamycin had no impact on radiation sensitivity.

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N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells. Bronchoalveolar lavage (BAL) revealed lymphocytic and neutrophilic alveolitis.

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The present review outlines the application of mathematical modelling to the dynamics of targeted cancer therapy, focusing particular attention on chronic myeloid leukaemia and its treatment with imatinib (Glivec). The incidence of cardiovascular mortality in diabetic subjects without a clinical history of previous cardiac events is as high as the incidence in nondiabetic subjects with a history of myocardial infarction. Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some of which govern neuroblastoma cell viability.

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Thought suppression and its effects on thought frequency, appraisal and mood state in individuals with obsessive-compulsive disorder. In a Pppas2 null mutant, import of both peroxisomal targeting signal 1 (PTS1)- and PTS2-containing proteins is impaired as shown by biochemical fractionation and fluorescence microscopy. Although the majority of research reports of power Doppler ultrasound assessment of the musculoskeletal system evaluated validity, less than half reported reliability and responsiveness. A tale of two signals: Wnt and Hedgehog in dentate neurogenesis.

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Thirty patients had anterior cruciate ligament reconstruction for ongoing instability. Repeated therapy led to the formation of small amounts of anti-mouse antibody, but provided that cyclosporin A was continued it did not prevent further therapy or lead to an increase in the rate of clearance of anti-CEA from blood.

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The handling of acute life-threatening choking in geriatric and nursing home patients Male and female 16 to 18 month old C3Hf/Bd mice in a dermal carcinogenicity study were moribund or died at earlier time points than the expected 24 to 30 months. Urinary E1C in the pregnant chimpanzee was higher than during the menstrual cycle and increased with advancing gestation, with maximum levels occurring near term.

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Outcomes were assessed using a sleep diary, as well as several standardized self-report scales. However, in spite of impressive progress in certain areas, much confusion and disagreement remain in regard to the management of the diabetic patient with end-stage renal disease.

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Our data suggest that routine CT evaluations are superfluous in acute sinusitis. Efficacy of trastuzumab was examined as a single agent or in combination with chemotherapeutic agents widely used clinically for gastric cancers in HER2-overexpressing human gastric cancer xenograft models.

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These subgroups often paralleled difference in the level of toxicity of the strains for mosquito larvae. Mean trophic level (MTL) of landings and primary production required (PPR) by fisheries are increasingly used in the assessment of sustainability in fisheries.

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Dynamic changes of DNA sequences in Schistosoma mansoni in the course of development. Qualities/characteristics preferred in continuing education instructors. We aimed to induce neural stem (NSC) and progenitor cells (NPC) from human placental tissues. Anti-inflammatory and anti-arthritic effects of water distillates of Ephedra sinica STAPF (ES), in herb-acupuncture, on the inflammatory responses of arthritis was investigated using phorbol 12-myristate 13-acetate (PMA)/lipopolysaccharide (LPS)-induced human macrophage and adjuvant-induced arthritic rat.

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Due to the limited capacity of dietary mixed micelles to embody hydrophobic sterol/stanol molecules, the micellar concentration of cholesterol is reduced and hence, its transport towards the intestinal brush border membrane decreases. We report histologically different gliomas occurring simultaneously in both the cerebrum and cerebellum in a 53-year-old woman. This was accompanied by an early induction of P38 MAP kinase, which is influenced by ROS and plays an important signaling role for induction of iNOS. The vessels at the base of villi, which is associated with lymphocyte recruitment, may become a site of intense immune reactivity in the early phase of small-bowel allograft rejection. AgNORs were studied by using a silver staining technique and image analysis system.

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Subsequent intramolecular attack would result in the 2,4-endoperoxy (di)anion that may collapse to the reaction products. Finally, dominant-negative plasmids encoding p38 and ERK transfected alone into the cells impaired the ATP-induced release of PGE(2) to about the same extent as both plasmids transfected together. We evaluated arthritides by clinical and histological assessment, and titers of neutralizing anti-hTNF-alpha antibody by enzyme-linked immunosorbent assay and L929 assay.

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The present study investigated the central role of hCG in this process by using antisense receptor phosphorothioate oligodeoxynucleotides (ODNs). Preliminary experiments suggest that slow temporal changes in the degree of synchronization are more useful in distinguishing between very similar odorants than is the spatial distribution of mean firing rate. Our results imply that even rare interpopulation migration can lead to the rescue and recovery of isolated and endangered natural populations. Survival was compared with that of the 51,434 Mayo Clinic patients with a QTc less than 500 ms during the same period.