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To analyze the extracellular proteolytic activities of a large number of Candida clinical isolates, we developed a screening system based on a solid medium containing hemoglobin as the sole nitrogen source. Self-rated pain and perceived health in relation to stress and physical activity among school-students: a 3-year follow-up. Leaf palisade cell development and the composition of chloroplasts respond to the fluence rate of light to maximise photosynthetic light capture while minimising photodamage. Among these, silica in straw forms a low-melting eutectic with potassium, causing slag deposits, and chlorides cause corrosion beneath the deposits. Terminal afferent lymphatics are continuous with the subcapsular sinus through oval holes, about 3 microns wide, along their length, and through larger openings near their end.

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Confocal microscopy revealed that MUC1 was uniformly distributed on the surface of activated T cells. Interferons (IFNs) stimulate gene expression to mediate their biological actions. The incidence of several epilepsy syndromes peaks in adolescence. Multiple infarcts were found in the abdominal organs and leg muscles. Effect of acupuncture on selective attention for smoking-related visual cues in smokers.

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They suggest recognition of multiple peptides and involvement of beta-chain junctional regions in recognizing shared motifs among some of these peptides. Ambulatory anaesthesia: questions about the preanaesthetic examination The mutants were characterized with respect to thermal and chemical stability, GTPase activity, tRNA affinity, and activity in an in vitro translation assay. These auditory sensitivities were compared with average spectra for (a) contact calls and (b) a general sample of vocalizations recorded from wild birds.

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We conclude that conversion of LC to OC is more prevalent among males and is probably attributable to a greater incidence of anatomical difficulties. In additional groups, kidneys were removed at the end of five days of obstruction. In all spinalized animals early balanced bladder function could be achieved, due to the absence of detrusor-sphincter dyssynergia: the opposite is true for spinalized man.

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Methylenecyclopropylcarbinols treated with sulfonyl chloride and Et(3)N form the sulfonated products in almost quantitative yields, which can be transformed to the corresponding 3-methylenecyclobutyl sulfonates with silica gel chromatography work-up. In order to mimic some aspects of the native cell membrane, a supported lipid membrane is formed on the QCM-D sensor surface. Evaluation of antiulcer drug binding to experimental ulcer sites.

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Correlation between clinical phenotypes and expression of several genes in the mitogenic limb of the insulin signaling pathway suggests mitogenic signaling by insulin may regulate steroidogenesis and glucose homeostasis. The dichroic absorption of the bR molecule is polarization dependent, thereby allowing for the recording of polarization holograms.

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In this study, the effect of polymerization time on the chromatographic, material, and chemical characteristics of poly(butyl methacrylate-co-ethylene dimethacrylate) monoliths was studied using pyrolysis-gas chromatography, Raman spectroscopy, inverse size exclusion chromatography, scanning electron microscopy, and chromatographic methods. Injectable formulation of Pantoprazole is about three times more stable than that of Omeprazole.

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Theoretical models of cognitive functions are proposed that link the molecular to the cognitive level. Twenty-one patients (age range 50-77 years, average 61.4 years) with negative TRUS biopsy were enrolled Suspicious areas were identified by discrete low signal intensity in T2 on standard MRI.

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The active mutant of SGK (D-SGK, substitution of Ser422 with Asp) and myr-SGK were shown to phosphorylate GSK3 and to enhance glycogen synthase activity in hepatocytes in a manner very similar to that observed for myr-Akt. To date, most studies have considered embarrassment and stigma in society and internalized by the afflicted individual but have not assessed family embarrassment in a large-scale study. Intravascular coagulation in chronic forms of ischemic heart disease (according to the data of radioisotope studies) Treatment periods lasted 4 months with a 1-month washout period between diets. The pharmacokinetics and sputum penetration of ampicillin and amoxycillin following simultaneous i.v.

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The new data suggest that nervous systems become more complex, not by one system invading another, but by a process of parcellation that involves the selective loss of connections of the newly formed daughter aggregates and subsystems. Ten healthy subjects were studied in the low-dose (30 mg x 2) limb and 11 healthy volunteers in the high-dose (80 mg x 2) limb. Marked discrepancy of applanation and indentation tonometry in infantile glaucoma is frequent. These results show impaired vocal pitch-matching abilities in amusics but also show a relationship between perceived and produced pitches. Consistent with these results, we found that the down-regulation of Notch-1 or Jagged-1 led to decreased expression and the activity of NF-kappaB downstream genes such as MMP-9, VEGF, and uPA, contributing to the inhibition of cell migration and invasion.

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The method provides high color contrast views, and also enabled us to examine inside the embryos. An out-of-plane component of the joint load causes higher prosthesis and cement stresses. The cDNA contains an opening reading frame of 315 nucleotides encoding 104 amino acid residues. The sections were stained with a double immuno-histochemical technique which utilised a keratin antibody AE1-AE3 (1:2,000) and an endothelial antibody Factor VIII (1:10,000) to enable simultaneous labelling of ERM and blood vessels.

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Group analysis of self-organizing maps based on functional MRI using restricted Frechet means. This reduction of search space substantially simplifies the algorithmic complexity. Does bevacizumab improve survival in patients with metastatic colorectal cancer treated with chemotherapy? Mechanisms of fibronectin and integrin function during cell adhesion and migration. damicornis ceased following 4 months of ammonium exposure and did not recover until 3 months after termination of nutrient enrichment.

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In control experiments, we found that neither attention nor eye movements can account for this illusion. Joint T1 and brain fiber log-demons registration using currents to model geometry. Bilateral sagittal knife cuts that bracketed the rostral pontine CG also eliminated lordosis, and an experiment with the retrograde tracer Fluoro-Gold confirmed the effectiveness of these cuts in severing the lateral connections linking the VMH and the CG. Plural transformation-processes from spiral to coccoid Helicobacter pylori and its viability. Cocaine and body temperature in the rat: effects of ambient temperature.

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In the aleurone cells, expression of these alpha-amylase genes was regulated by gibberellins produced in the embryo and by osmotically active sugars. Polysialic acid (PSA) capsules are cell-associated homopolymers of alpha2,8-, alpha2,9-, or alternating alpha2,8/2,9-linked sialic acid residues that function as essential virulence factors in neuroinvasive diseases caused by certain strains of Escherichia coli and Neisseria meningitidis.

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Elevated 5-ene-steroid excretion was also observed in several patients with normal serum 5-ene-steroids. However, this test is subject to interference by strong oxidants, certain transition metal ions, and true peroxidases. Our understanding on cell dynamics built from snapshots on fixed specimens has evolved thanks to our actual capability to monitor in real time the evolution of processes in living cells. Then the rats received an IP injection of a furosemide to develop sodium deficiency. Interactions of bupivacaine with a molecularly imprinted polymer in a monolithic format studied by NMR.

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MiR-92b expression was significantly increased in high-grade gliomas compared with low-grade gliomas, and positively correlated with the degree of glioma infiltration. Developmental changes in expression of alpha-tocopherol transfer protein (alpha-TTP) after birth were investigated using rats with respect to plasma changes of tocopherols. The phenotypes of the mutants in these three assays suggest that small T antigen has at least three separate functions. Solubilization and desorption of PAHs in soil-aqueous system by biosurfactants produced from Pseudomonas aeruginosa P-CG3 under thermophilic condition.

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The current work complements prior reports of positive implementation outcomes and intervention effectiveness for the parent trial, mapping qualitative managerial accounts of this contingency management intervention to a set of attributes thought to influence the speed and effectiveness with which an innovative practice is disseminated. We have studied the effect of TLR7/8 agonists on DC differentiation and maturation from human monocytes. During the follow-up 33,851 malignancies was recorded 1988-1999. Primary cultures of KFs and surrounding nonlesional fibroblasts (NFs) were subjected to induction or inhibition of IL-6 or its specific receptor IL-6 receptor alpha (IL-6R alpha) and detection of their effects on extracellular matrix gene expression.

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Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney disease (CKD). In vivo characterization of extracellular GABA release in the caudate nucleus and prefrontal cortex of the rhesus monkey.

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Anorectal pressures and rectal sensation can be conveniently measured by portable manometry and are significantly correlated with high-resolution manometry. However, the higher correlation between peer and teacher ratings of behaviors relevant to hyperactivity than between peer and parent or teacher and parent ratings supports the view that hyperactive-inattentive behavior is determined interactively by the person and the situation, rather than being a context-general trait. Sediments of San Diego Bay (SDB) are known to contain elevated levels of polychlorinated biphenyls (PCBs). The Src family kinases (SFK) and insulin-like growth factor-1 (IGF-1) signaling axes are aberrantly activated in both primary PCa and bone metastases and regulate distinct and overlapping functions in PCa progression. Modern approaches to the diagnosis and treatment of craniocerebral trauma and its sequelae

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However, morphometric analysis revealed a greater endplate complexity in treated animals in which, at 60 days after nerve crush, nerve terminal branching and sprouting index values were significantly higher than in controls. This correlation in aneuploid melanomas partially explains the correlation between nuclear size and melanoma thickness. To confirm the diagnosis, we performed an incisional biopsy of the eyelid. This may indicate disturbances in the integrated motor unit activity.

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PTC is an appropriate destination for severely injured adolescents. The GP is less often convinced of a causal connection between both than the patient. The experimental evidence on RIBE, indicate that a more analytical and mechanistic in depth approach is needed to secure an answer to one of the most intriguing questions in radiobiology. These glands were observed in FPSHs, although in a variably atrophied form. Whereas metals and polymeric brackets allow some deflection of the material in addition to the tensile stress, separating the bracket from the enamel at the bracket-to-adhesive interface, or within the adhesive composite, the lacking workability in the ceramic brackets may induce a shift of the break-line during debonding to the adhesive-enamel interface or even into the dental enamel.

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Simulation of the human neuromuscular response to ankle rotation with a segmental reflex model. Counselling of mothers should include an assessment of individual and environmental criteria to support appropriate infant-feeding choices. Prognostic factors and treatment of acute lymphoblastic leukaemia (ALL)--Istanbul experience. We determined how well the symptoms of OAB syndrome correlate with urodynamic DO using International Continence Society definitions. Magnetic resonance imaging of the brain showed aqueductal stenosis associated with moderate supratentorial hydrocephalus, and erosion of the cribriform plate.

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Venous thromboembolism risk and prophylaxis in the acute care hospital setting (ENDORSE survey): findings in surgical patients. Clinical symptoms of BO were cough, tachypnea, and wheezing after acute lung injury. Pathology results demonstrated nocardial infection, initially advanced despite antibiotic therapy. A simple purification procedure for rat pancreatic elastase and radioimmunoassay of the enzyme.

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Hypoglycemia in children may be considered a risk factor for brain damage and later intellectual impairment, and carries with it a high degree of child and parental anxiety. Consistent lesions associated with coccidia in piglets not infected by other primary enteric pathogens suggest that coccidia are the cause of significant clinical disease in nursing piglets 6 to 15 days old. We carried out a resequencing project that examined 552 kb of sequence from each of 46 individual HLA haplotypes representing a diversity of HLA allele types, generating nearly 27 Mb of fully phased genomic sequence. High count rates with total internal reflection fluorescence correlation spectroscopy. Surgical correction in infants born with transposition of the great arteries, venous rerouting procedure (Mustard or Senning operation) or an arterial switch operation, can be complicated by vascular narrowings.

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This is the first detailed report of toxoplasmosis in black-footed ferrets. The voltage dependent characteristics of the neurons suggest that a prolonged afterhyperpolarization due to an outward potassium current and a low-threshold calcium conductance contributed to these two modes of firing.

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Chronic exposure to U46619 resulted in a concentration-dependent increase in protein expression of p160ROKI that was inhibited by pre-treatment of the cells with the C3-exotoxin. Do pre-existing diabetes social support or depressive symptoms influence the effectiveness of a diabetes management intervention? This results in the inhibition of caspase-9 and -3 and apoptotic cell death in PC12 cells by suppressing the toxic actions of reactive oxygen and nitrogen species, including the GSH depletion.

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Furthermore, by SIRMS-generated spectra, it was found that CALB secondary structure was not altered by immobilization. In parallel, specific oligonucleotides were used to detect the mRNA levels of caspase family members. New member of the multigene family of complement control proteins in herpesvirus saimiri. The regulation of vaginal bleeding is an important effect impacting the choice of contraceptive methods. Ultimately, the principal endeavor of introducing the measurement of tumor burden, in both experimental and clinical oncology, may be to achieve a better assessment of the inter-individual variation in the host vulnerability to cancer cachexia.

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The aim of this work is to evaluate the outcome of bipolar hip arthroplasty as a salvage procedure for treatment of loosening of the acetabular cup with significant acetabular bone defects after total hip replacement (THR) in multi-morbid patients. (b) Who talks to whom?, ie making sense of the molecular interactions in a context-dependent way. Newly-diagnosed pediatric epilepsy is associated with elevated autoantibodies to glutamic acid decarboxylase but not cardiolipin.

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Brevibacterium casei bacteremia and line sepsis in a patient with AIDS. Axillary nerve repair by triceps motor branch transfer through an axillary access: anatomical basis and clinical results. Effective treatment of hypertension requires continued prescribing of antihypertensive medications for many years.

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PEDF dose-dependently inhibited the brain edema, whose effect was neutralized by simultaneous treatments with anti-PEDF Abs. Within this period the endo-RNAase activity was markedly decreased in membrane-bound polyribosomes but the enzymatic activity was increased in free polyribosomes. Effects of 1alpha,25 dihydroxyvitamin D3 on the expression of HO-1 and GFAP in glial cells of the photothrombotically lesioned cerebral cortex. Simultaneous measurement of plasma concentrations and 13C-enrichment of short-chain fatty acids, lactic acid and ketone bodies by gas chromatography coupled to mass spectrometry.

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Throughout the period studied the random component of inbreeding (F(r)) has not changed, in contrast to the non-random component (F(n)), thus suggesting the latter could be responsible for the reduction of total inbreeding. (18)F-FDG PET/CT demonstrates high diagnostic accuracy for detecting recurrence in patients with primary skeletal Ewing sarcoma, when it is suspected (clinically or on imaging) or during routine follow-up. Hepatotoxicity caused by Ecstasy is increasingly important, particularly in young adults. Neuronal circuits in the central nervous system play a critical role in orchestrating the control of glucose and energy homeostasis. In exceptional situations not covered by legal provisions, doctors may want to waive confidentiality against the wishes of the patient.

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The CLOCK gene is one of the core genes regulating circadian rhythms and shows significant expression on 7 d post-C. Domain scaling and glassy dynamics in a one-dimensional Kawasaki Ising model. In this paper, we use a constrained mixture theory for growth and remodeling of planar soft tissues to motivate a new experimental approach for investigating competing hypotheses on, for example, how new collagen is aligned by synthetic cells. Serum SIL-2R levels in the patients with active uveitis were significantly higher than that in the controls, but there were no significant difference among anterior uveitis, intermediate uveitis, Behcet disease and Vogt-Koyanagi-Harada syndrome.

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Time-correlated single-photon counting is used to produce time-dispersion curves, which one fits to the diffusion equation to determine absorption and reduced scattering coefficients. Oligosaccharyl transferase (OT) is a multisubunit enzyme that catalyzes N-linked glycosylation of nascent polypeptides in the lumen of the endoplasmic reticulum. Thermodynamic data calculated suggests that the R(CS)NH2 and R(CO)NH2 species are more stable than the R(CNH)SH and R(CNH)OH species. Hemodynamic parameters and NT-proANP concentrations were assessed during the early and late second trimester, the third trimester, and after delivery in 20 women with essential hypertension and 30 normotensive women.

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Uptake and toxicity of glyphosate in the lichen Xanthoria parietina (L.) Th. These comparative analyses have been extended to a number of genes involved in antioxidative, wounding or pathogenesis responses, showing several differences among cultivars that could be related with their different sensitivity to ozone. The clinical duration of neuromuscular blockade and the recovery times were slightly prolonged, due to significantly reduced serum cholinesterase activity (clinical duration 24.6 min vs. They discuss the role of urinary tract infection in the occurrence of hemolytic uremic syndrome and the possible role of specific Escherichia coli strains. L-ascorbic acid is one of the basic vitamins, necessary to the normal growth and behaviour of organisms.

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No not only is a potent vasodilator, it also inhibits platelet adherence and aggregation, reduces adherence of leukocytes to the endothelium, and suppresses proliferation of vascular smooth muscle cells. Failure to complete the hearing screening follow-up may be related to cultural differences that have been previously reported in other maternal and child health studies of the diverse populations in Hawaii. Species-specific as well as total Cer-SPM ratios were increased, whereas LPC-PC ratios were decreased in sepsis patients. Although cervical and lumbar disc replacements are in their spinal surgical infancy with regard to clinical application, the indications are already delineated. A central question in neuronal network analysis is how the interaction between individual neurons produces behavior and behavioral modifications.

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Massachusetts General Hospital/Harvard Medical School MD oral and maxillofacial surgery program: a 30-year review. Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy. The use of these ratios will enable reproducible intersubject and interclinic quantitation. We used the Alu PCR products from a pair of somatic cell hybrids in which the human DNA content differs only in the 5q11.2-q13.3 region as differential hybridization probes.

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Involvement of N-cadherin in the protective effect of glial cell line-derived neurotrophic factor on dopaminergic neuron damage. The gamma-tubulin spots were not detected until the 8-cell stage of parthenotes. 5) It is cost effective to prevent nosocomial infections even at higher cost.

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thermophilus C5 was further shown to be dispensable for RNase P function in vitro by using a precursor tRNA(Gly) substrate from the same organism. Effect of cell density and confluency on cholesterol metabolism in cancer cells in monolayer culture. Because of the limited bandwidth of the channels, such random packet losses could occur, simultaneously, in the communication channels from the sensor to the controller and from the controller to the actuator. Those who died of burns (average age 76.4) had burns over 44.8 percent of the mean body surface, whereas the survivors (average age 73.5) had burns over a smaller area (16.7 percent).

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The development of normative data for these structures and the simplicity of the methodology should have many clinical applications in the assessment of aberrant brain development. This knowledge may contribute to more individual adept child accident prevention programme, to use in the child health care. High-frequency activation of an afferent excitatory fibre system can induce long-term potentiation, and conjunctive activation of two distinct excitatory synaptic inputs to the cerebellar Purkinje cells can lead to long-term depression of the synaptic activity of one of the inputs. Glass and plastic photoluminescence: interaction with aqueous media and cultured mammalian cells.