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Topimax (Topiramate)
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Topiramate

Topimax is a medication that works in the brain and is sometimes used in patients with bipolar disorder (also known as manic depression). It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults. Bipolar disorder involves episodes of depression and/or mania.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Despite considerable structural and biophysical research, the mechanism behind activation of the NMDA receptor is still poorly understood. Less is known of the comorbidity of other somatic symptoms with headache. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1870004378817301. One population of Tax is tightly associated with nuclear speckles. By retrospective simulation of 32 donors and 613 recipients in the Nord Italia Transplant area, matchable recipients were available for all donors, while blood group frequency seemed a determining factor, more than donor body weight.

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Carbon nanobeads seems to absorb the microwave in the range of 8-12 GHz. Cross-linking experiments with a water-soluble carbodiimide revealed that mutagenesis of residue D9 led to the disruption of an intramolecular salt bridge.

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The results of this study support the existence of tumor suppressor gene(s) on 1p associated with recurrence in meningiomas and suggest that status of chromosome 1p by FISH may assist physicians in predicting prognosis of patients affected by this tumor. The patterns suggest that networks shrunk because (1) social network members died prematurely, (2) study participants withdrew or pushed others away, and (3) friends and family members faced so many obstacles of their own that they could not provide resources for the study participants. Effects of anticoagulants on Plasmodium vivax oocyst development in Anopheles albimanus mosquitoes. Japanese cedar is a major species grown in artificial Japanese forests, and its thinning is crucial for the health of artificial forests and the Japanese economy.

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The apparent discrepancy between the changes in serum and urine levels of TATI may be explained by the very short (6 min) half-life of TATI in serum. In addition, in vitro acid killing and pH drop experiments were used to detect the role of ureolysis in bacterial aciduricity and capacity to modulate pH homeostasis.

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Independent sources of anisotropy in visual orientation representation: a visual and a cognitive oblique effect. This study provides an approach to rapidly characterize bioactive constituents in traditional Chinese medicines (TCMs).

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The study also aimed at providing a scientific rationale for the traditional use of plant combinations to treat skin diseases and the isolation of the bio-active compound from the most active species, Aristea ecklonii (Iridaceae). Ethicists have suggested that written consent forms encourage participants in phase 1 cancer trials to expect benefit from the experimental agent and to overlook serious risks. We further showed that the colon cancer cell line expressing the wild-type APC gene was more sensitive to a DNA-methylating agent due to decreased DNA repair by long patch BER than the cell line expressing the mutant APC gene lacking the proliferating cell nuclear antigen-interacting protein-like box. The successful stitching relies heavily on the accuracy of corner selection. In both locations, these WT signatures were associated with asymptomatic BNYVV infections of Rz1 cultivars.

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Early continuous high-volume-hemofiltration has significant effects on the treatment of SAP including the improvement of clinic symptoms, the blockade of development from systemic inflammatory response syndrome (SIRS) to multiple organ dysfunction syndrome (MODS), improvement of organ function and prevention from the complications. In contrast to the activity profile of CK-II, we find that cyclic AMP-dependent protein kinase is rapidly inhibited upon serum-stimulation of WI38 cells. Motor effects of loperamide on rat urinary bladder: an in vitro study. Mefenamic acid affects the remaining parameters similarly to strophanthin, while dexamethasone inhibits them.

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All the cases achieved good results in urination with normosthenuria and normal force of urinary stream. Recovery and enumeration of Cryptosporidium parvum from animal fecal matrices. Brain cysts from three strains of Toxoplasma gondii were purified and analysed by SDS-PAGE and immunoblotting. The mechanism of action for this protective effect did not seem to be related to merely absorption and screening, inhibition of the inflammatory reaction or a UV-induced effect on the stereo-isomerization of the drug. IUC includes copper-containing intrauterine devices and levonorgestrel-releasing intrauterine systems.

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A jumping-drop superhydrophobic condenser minimized frost formation relative to a conventional dropwise condenser in two respects: preventing heterogeneous ice nucleation by continuously removing subcooled condensate, and delaying frost growth by limiting the success of interdrop ice bridge formation. EEG characteristics were related to clinical items and to a serotonin re-uptake indicator. The present research aims at establishing whether there exists any relationship between BMI and colorectal cancer in Poland.

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However, the purported rhamnogalacturonase B (RGase B) is, in fact, an endolyase that cleaves the -2)-alpha-L-Rhap-(1-4)-alpha-D-GalpA glycosidic linkage, thereby generating oligosaccharides terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue. Despite lower platelet reactivity of prasugrel compared with clopidogrel, no treatment interactions for ischemic and bleeding outcomes were observed.

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All parameters describing the circulating platelet biomass except the platelet volume heterogeneity were decreased in these patients. Although the 20E effects are relatively well known, the physiological relevance of its receptors remains poorly understood. Moreover, inhibition of MAPK signaling blocked progesterone-induced Mos protein accumulation. We evaluated the clinical impact of some prognostic factors, known being important in the advanced lesions, in a series of EGC patients with special reference to the clinicomorphological features.

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2,5-DKGR, as with most other members of the aldo-keto reductase (AKR) superfamily, exhibits a preference for NADPH compared to NADH as a cofactor in the stereo-specific reduction of substrate. Factors influencing the differentiation of embryonal carcinoma and embryo-derived stem cells.

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From heterogeneity chi 2 tests, it was evident that the differentiation observed was largely attributable to five sites which were located in the semiarid eastern region, whereas haplotype frequencies were homogeneous throughout the arid western region. A portable anodic stripping voltammetry (ASV) instrument was evaluated utilizing paired samples from 243 employees working at an elevation of approximately 3,800 meters in Peru.

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Although diagnosis is easily achieved by CT sean, atypical forms may lead to the wrong diagnosis of cerebellar hematoma. After activation, which requires activity of postsynaptic NMDA (N-methyl-D-aspartate) receptors, neurotrypsin cleaves the heparan sulfate proteoglycan agrin at active synapses. Genotyping revealed the presence of the frame-shift mutation 138delT only in those subjects who expressed the brain variant CYP2D7, which metabolizes codeine exclusively to morphine unlike hepatic CYP2D6 that metabolizes codeine to nor codeine and morphine. Bronchial arteriography for the diagnosis of massive hemoptysis uncontrolled by medication: report of 2 cases This is, to our knowledge, the first report of a stimulatory action of MDL 12330A on an adenylyl cyclase system.

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FITC-lectins specific for N-acetylglucosamine, N-acetylgalactosamine and mannose/glucose were readily bound by trophozoite and cyst surfaces. Helicobacter pylori antibodies in patients on chronic hemodialysis. Although these agents have a preservative action, it was recently demonstrated that, after short or long term use, toxic side effects on the ocular surface will occur. In particular, the applications of nanomaterials in biological systems are attracting considerable interest because of their unique, tunable, and versatile physicochemical properties. After a range of doses of irradiation, SRC-3(-/-) mice exhibited lower counts of peripheral blood cells and bone marrow (BM) mononuclear cells and excessive BM depression, which resulted in a significantly higher mortality compared with wildtype mice.

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Current legal developments in medical staff credentialing disputes. A variety of designs of ileal pouch are available each with advantages and disadvantages. Obesity contributes to insulin resistance and is a risk factor for diabetes.

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The enhanced nonlinear optical properties of Graphene-6THIOP should be attributed to the combination of the observed nonlinear scattering with the possible photoinduced electron or energy transfer mechanism between 6THIOP moiety and graphene. Cloning and expression patterns of the brine shrimp (Artemia sinica) glycogen phosphorylase (GPase) gene during development and in response to temperature stress. A few INC-RF projections were observed to low thoracic and lumbosacral levels.(ABSTRACT TRUNCATED AT 400 WORDS)

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Although the measurement of coronary flow velocity (CFV) reserve (CFVR) in the left anterior descending coronary artery (LAD) by transthoracic Doppler echocardiography has been established, its success rate in the posterior descending coronary artery (PD) is still limited. Dipyridamole was also found to directly affect the scavenging of active oxygen metabolites generated by opsonized zymosan-stimulated human PMN at therapeutic concentrations.

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Children with attention-deficit hyperactivity disorder (ADHD) and depression were more likely to have been victimized, whereas children with conduct disorder (CD) or oppositional defiant disorder (ODD) were more likely to have bullied other children. Our results indicate that Cux-1 is a useful marker of the layer IV neurons in S1, and that Cux-1 and Cux-2 are differently regulated in the upper layers of the cerebral cortex. In this small study, continuous low-level heat wrap therapy was of significant benefit in the prevention and early phase treatment of low back DOMS. The role of cell-cell adhesion in the transition from premalignancy to invasive cancer is not well understood. Manual and automatic segmentation times were recorded, and LV masses determined with each were compared with each other and with the true LV mass at autopsy.

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Temporal resolution and the evaluation of candidate algorithms for four-dimensional CT. Age-dependent association between IgG2 and IgG3 subclasses to Pf332-C231 antigen and protection from malaria, and induction of protective antibodies by sub-patent malaria infections, in Daraweesh. Dose-response relation of gallopamil in comparison with nifedipine, diltiazem and tiapamil in patients with coronary heart disease Characterization of mice rendered deficient in eukaryotic initiation factors has provided model systems to study the involvement of translation in regulating insulin synthesis and secretion, hepatic function, peripheral insulin resistance, and diabetic complications. Phenotypic analysis indicated that both alpha-hemolysin level and fibrinogen-binding capacity were up-regulated in the mutant strain compared with the parental strain.

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These findings are discussed with a focus on current ramifications and the implications for future research. Many experiments have shown convincingly that natural killer (NK) cell activity against viral infections is an important early defence mechanism in mice. Liver function was assayed by alanine transaminase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) release as well as output of bile flow. Confirmatory analysis using seed-based voxel correlation was performed.

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Secondary hypertension in overweight and stage 1 hypertensive children: a Midwest Pediatric Nephrology Consortium report. 7-alpha-Dehydroxylation of primary bile acids was demonstrated radiochromatographically in whole cells of Clostridium leptum but was not observed in intestinal Bacteroides species. The sexual concerns of the adolescent woman with cerebral palsy. We performed this study to clarify natural consequences of abnormal structures (stent malapposition, thrombus, tissue prolapse, and stent edge dissection) after percutaneous coronary intervention (PCI). These gene mutations have been detected and their dysfunction may lead to accumulation of genomic alterations.

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Earlier studies have been confined to antibodies specific for small molecules (haptens) rather than for proteins. Likely due to enlarged SAMs, fon4 mutants produced thick culms (stems) and increased numbers of both primary rachis branches and floral organs.

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Prostaglandin F2alpha (PGF2alpha)-induced contraction and calcium movement in longitudinal muscle of guinea-pig isolated stomach. The combined use of four treatment modalities for calciphylactic ulcers--all of which have proved effective on an individual basis--may provide the optimal treatment approach. It is concluded that bradykinin and FMLP affect pyeloureteral motility through specific and independent pathways. Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure.

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The combined use of whole-plasmid analysis, restriction enzyme analysis of plasmid DNA with two enzymes, and contour-clamped homogeneous electric field electrophoresis with two restriction enzymes should be considered when E. Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy. In this study, we identified RSV effects on interferon (IFN)-dependent signal transduction and gene expression in human airway epithelial cells.

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Lymphangioma or cystic hygroma (CH) in neonates is a rare congenital malformation (1:12000 live births), its etiology is unknown. Recent theorizing indicates that the acquisition of movement sequence skill involves the development of several independent sequence representations at the same time. We have investigated the binding kinetics of PH domains found in the tail region of the molecular motor, myosin X.

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The spindle checkpoint in the yeast Saccharomyces cerevisiae is an intracellular signal transduction pathway comprised of two branches that inhibit two different mitotic transitions in cells treated with benzimidazole drugs such as nocodazole. The present study investigated whether the existence of this organelle in follicular cells is a general event in the postnatal thyroid gland of different mammals, using both immunolabeling by immunofluorescence and electron microscopy.

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Significance: Traditional therapies, including the use of dietary components for wound healing and skin regeneration, are very common in Asian countries such as China and India. A diagnosis of schizophrenia, being identified with any indicator of risk or illness severity, and being prescribed with depot injectable antipsychotic medication was associated with the lowest likelihood of prescribing. Extrapleural pneumonectomy for relapsed solitary fibrous tumors of the pleura with pleural dissemination Thus, the Ad8 epidemics of 1983/1984, 1984, 1987, and 1988 appear to have been due to DNA variants Ad8/D7, D8, D9, and D10, respectively.

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The great majority of these symptoms all occur in the absence of occlusive disease. They had been diagnosed with PCOS between 1984 and 1990 when they were 13-18 yr. Mistreatment exists due to its cyclical nature and the existing culture of medical training. Evaluation of inflammatory change and bone erosion using a murine type II collagen-induced arthritis model.

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The use of epidural anesthesia reduced the incidence of proximal thrombosis after both unilateral and one-stage bilateral arthroplasty. Control system architecture for a minimally invasive surgical robot. This surgical therapy has been certainly improved by the introduction of the laparoscopic techniques, which allowed us to exert bilateral adrenalectomies in two times with a significant reduction of perioperative morbidity and mortality because of the less severe traumatism and the absence of addisonian complications. Internal fixation of fractures of the dorsal-lumbar spine with early ambulation is evaluated in this study of 100 patients with 106 fractures: 34 being treated by recumbency, 13 with Meurig-Williams plates, and 59 with Harrington rods.

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Growth hormone (GH)-secreting adenomas tent to have higher absorption coefficient on plain CT than the nonfunctioning and prolactin (PRL)-secreting adenomas. Although the series of cell lines studied provided a broad spectrum of LETS protein expression, both quantitatively and qualitatively, there does not appear to be a correlation between tumorigenicity and decreased expression of the LETS protein. In this portion of the article, Part I, population models are presented. The presence of SAP D was confirmed by Western blotting and of SAP A by protein sequencing. S1P is among the few endogenous HDAC inhibitors that is synthesized in the nucleus in response to extracellular stimulation, and the first nuclear lipid associated with an epigenetic modification.

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Whereas cyclic AMP has been described as a link between atopic and affective disorders, a possible link between atopic disorders and schizophrenia has not yet been investigated. OntoPIN allows: (a) to extend existing PPI databases by using ontologies, (b) to enable a key-based querying of annotated data, and (c) to offer a novel query interface based on semantic similarity among annotations. Only by being well informed will a woman be able to decide intelligently what therapy would best protect her from osteoporosis. An ultrastructural study of bacterial invasion and tissue breakdown in human experimental root-surface caries. Furthermore, combination therapy is being explored with these various new antifungal agents.

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Exposure to benzene would cause bone marrow depression presenting as drop in hemoglobin, hematocrit and eosinophil counts. IE susceptibility rapidly decreased between 0 to 6 h after catheter removal. Here we propose a hypothesis that gap junctions functionally couple the epithelial cells of Malpighian tubules, resulting in a coordinated physiological response to the binding of neuropeptides. Even in Group A, side effects were less severe than effects normally associated with systemic chemotherapy. Here, we investigated the p53 mutational status in 138 B-CLL samples and compared these findings with drug and gamma-irradiation sensitivity profiles.

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In vitro chemosensitivity testing of leukemic cells: development of a semiautomated colorimetric assay. To compare dominant learning styles of pharmacy students and faculty members and between faculty members in different tracks. Thin films made of the nanofibers have superior performance in both sensitivity and time response to vapors of acid (HCl) and base (NH3). suis strains with gastric disease in humans, thus emphasizing the zoonotic importance of H.

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A less invasive method to assess internal thoracic artery (ITA) graft function after coronary artery bypass grafting (CABG) is desired. Age, sex, weight, type of production, and environment of the cattle also should be considered in choice of therapy.

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Genetic determinants of non-insulin-dependent diabetes mellitus: strategies and recent results. This pilot study examined the integrity of the corpus callosum in a sample of patients with borderline personality disorder (BPD), as abnormalities in inter-hemispheric communication could possibly be involved in illness pathophysiology. This study showed no significant difference in the epidemiology of pancreatic involvement between Japanese and non-Japanese VHL patients. Examples include the overexpression of FGF2 and FGF6 in prostate cancer, and FGF8 overexpression in breast and prostate cancers. The anthraquinone dye reactive blue 2 was found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids.

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Periarticular calcification after intra-articular triamcinolone hexacetonide. Simple risk predictions for arteriovenous malformation hemorrhage.

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Also, this method made it possible to distinguish between DNA modifications induced by the therapeutically fluconazole tablet cost active cis-diamminedichloroplatinum (II) (cis-DDP) alone, and those induced by its therapeutically inactive trans-isomer (trans-DDP). Application of the proposed methodology, complementary to the established targeted urine screening for known anabolics, will increase the chance of finding unknown emerging designer steroids, rather then being solely dependent on findings of the illicit preparations themselves. We have demonstrated that our stable water-dispersed nanoceria delay photoreceptor cell degeneration in rodent models and prevent pathological retinal neovascularization in vldlr mutant mice. Structures of the 2-nitrophenol alkali complexes in solution and the solid state.

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Upon ligand binding, Notch receptors undergo proteolytic cleavage leading to the release of their flomaxtra contraindications meaning intracellular domain (NICD). Quantum differences of ortho/para H2O2 spin-isomers as a factor of the femtosecond charge separation kinetics modulation in reaction centers of purple bacteria Preparation of some novel heterocyclic compounds with long alkyl and alkenyl chain of cytotoxic activity. The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

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A new biological glue for cartilage-cartilage interfaces: tissue transglutaminase. Side-to-end trigeminal to trigeminal fascicular neurorrhaphy to restore biomox vs clavamox lingual sensibility: a new technique.

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Three other genes showing statistical evidence (ADH1C, SCN3B, and IMP5) were not expressed glevo tabs in the embryonic tissues examined here. Our observation confirms that parkinsonism and sleep disorders may be consequences of encephalitis, that an immune-mediated pathogenesis is likely, and, consequently, that immunotherapy can be beneficial in these patients. In the 5 cases investigated the skin biopsy showed the same MAS deficiency histochemically in the granular layer of the epidermis as in the trophoblast cells. These lesions are rare and difficult to distinguish from the spongiosum tissue.

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Hyperoxaluria in patients with primary distal renal tubular acidosis. Distributing KI pills to minimize thyroid radiation exposure in case of a nuclear accident in France. After twelve days, approximately 7 ml ascetic fluid was harvested from the peritoneum of each mouse. Among the 28 per cent of farmers who replied, those who did castrate calves used one or more of three methods: the Burdizzo was used by 43 per cent of farmers, surgery by 39 per cent, and rubber rings by 32 per cent, with 10 per cent using more than one method. Cry4B was expressed omastin medicine ball weakly from An11S4::cry4B, but no expression of the binary toxin gene could be detected from An11S4::Omega::bin.

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Three compounds showed significant inhibition of PAD4 and their IC50 values were investigated. Media conditioned by culture of either metrial gland explants or migrating GMG cells terazosin hydrochloride usp monograph 88 were evaluated for various cytokine activities.

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Effective suppression of the anti-antibody response is possible and this study has determined that myelosuppression is the principal obstacle to repeated therapy with radiolabelled antibody. The porous particles could have unimodal or bimodal pore-size distributions and intraparticle convective fluid flow and pore diffusion are considered. We also show that the temperature extraction from BOTDA measurements employing ANN is significantly faster than the other citrol cleaner where to buy two approaches.

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The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique. The incidence of discontinuation-emergent adverse events was low and there were no statistically significant differences nupentin dosage of tylenol between the patients abruptly discontinuing from atomoxetine and those continuing on placebo. Human nonhematopoietic umbilical cord blood stem cells (nh-UCBSCs) were administered via tail vein to rats 2 days after infarct surgery.

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