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Soviclor (Acyclovir)
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Acyclovir

Soviclor is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Soviclor is converted to an active form by the virus itself, and the virus then uses the active form of Soviclor rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Soviclor into new viral DNA stops the production of the DNA. Virally infected cells absorb more Soviclor than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Soviclor in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Better understanding the mechanisms of leptin resistance should facilitate therapeutic approaches to reverse the phenomenon of selective leptin resistance. These studies support a functional role for endogenous endothelin as a potentially pathophysiological vasoconstrictor peptide hormone in the regulation of cardiovascular, renal, and endocrine function. We have examined the effect of amino acid substitution(s) in this region on T7 phage growth and on the interaction of the polymerase with thioredoxin. Molecular characterization of well-differentiated human thyroid carcinomas by cDNA arrays. With the use of a structured interview schedule, in-home interviews were conducted by a Hmong or a Cambodian bilingual staff person with the adult having primary responsibility for family meal preparation.

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The transfer of molecules between cells during cognate immune cell interactions has been reported, and recently a novel mechanism of transfer of proteins and genetic material such as small RNA between T cells and antigen-presenting cells (APCs) has been described, involving exchange of extracellular vesicles (EVs) during the formation of the immunological synapse (IS). Thin-section chest CT findings in polymyalgia rheumatica: a comparison between with and without rheumatoid arthritis.

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The problems and possibilities inherent in attempting to couple these components into a generic model of productivity are discussed. To describe a family pedigree with a previously undescribed association of autosomal dominantly inherited ocular abnormalities. Effects of a long-term spaceflight on immunoglobulin heavy chains of the urodele amphibian Pleurodeles waltl. These results suggest that colonoscopy should be the method of choice in colon cancer screening. The present systematic review involved studies conducted in recent years to analyze the knowledge, attitudes and behavior of Malaysian healthcare providers regarding breast cancer, in attempts to obtain an overall picture of how well equipped our healthcare providers are to provide optimal breast cancer education, and to see their perceptions and actual involvement in said education.

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Calcium-dependent nonspecific permeability of the inner mitochondrial membrane is not induced in mitochondria of the yeast Endomyces magnusii. Malnutrition in patients with CP is not just a complication of this disease, but has an important impact on its course. These analyses should preferably consider multiple perspectives and allow for the fact that the majority of the benefits accrue in the long-term future. We propose that in cases where this minimum plasma phenylalanine level is not reached, plasma tetrahydrobiopterin should be measured or alternatively other symptomatic family members should be screened. To eradicate Helicobacter pylori before the occurrence of precancerous changes is important to prevent gastric carcinogenesis.

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A prospective study of the roles, responsibilities and stresses of chaplains working within a hospice. A further series of experiments is necessary to elucidate the pathophysiological role of leptin in the differentiation of gastric adenocarcinoma. Superior labrum, anterior-posterior lesions and biceps injuries: diagnostic and treatment considerations. The dynamics of a periodically delta-kicked Hamiltonian system moving at low speed (i.e., at speed much less than the speed of light) is studied numerically.

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The rDFC induced by SV40Tag gene could be cultured and passaged in vitro, which retained the stable proliferation and differentiation characteristics and could be used for periodontal tissue engineering research. The mortality attributable to smoking and alcohol consumption decreased in the city of Barcelona during the study period. The characteristics of eosinophilic ureteritis and idiopathic segmental ureteritis are sufficiently overlapping and so uncommonly reported as to raise a nosological issue.

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Human superoxide dismutase A of the common phenotype SOD A1 is present in two electrophoretic forms in erythrocytes. Prevalence of substance abuse among regular degree health science students in Sheba University College in Mekelle Town, Tigray - Ethiopia. After acid activation of the samples, TGF-beta activity was found in the supernatants of all three mammalian ciliary epithelial cells. Forty human permanent molars with occlusal caries in dentin were selected, embedded in polyester resin, and ground until the carious dentin was exposed.

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Ionizing radiation and doxorubicin both produce oxidative damage and double-strand breaks in DNA. Thermally activated flux avalanches in single crystals of high-Tc superconductors. It is proposed that PsbS controls the macro-organisation of the grana membrane, providing an explanation of its role in NPQ. Flow cytometry analysis showed that PL increased the populations of both apoptotic sub-G1 and G2/M phase.

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After in vivo NE treatment, the expression of the mRNA of the transcriptional factor of IL-6, C/EBP-beta, was elevated earlier (after 45 min of NE infusion) than IL-6 mRNA (after 4 h) and was seen in MCs and NMCs. Besides the Bcl-2 proteins, the mitochondrial organelle contributes to and possibly regulates MOMP, because mitochondrial resident proteins and membrane lipids are prominently involved in the process. Nasal polyposis (NP) in adult population is a common problem in otorhinolaryngology outpatient practice. Information provided by angiogenic factor levels seems to be independent of and is possibly complementary to that provided by conventional serum markers. The discussion reviews the condition of polyarteritis nodosa and analyses the diagnostic difficulties in this case.

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No studies have addressed the spatial complexity of Anopheles arabiensis populations in Zambia or the effects of drought on the genetic structure of this species. Screening for retinopathy of prematurity: does one size fit all?

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Early identification of true responders to acid suppression in functional dyspepsia patients with symptoms of epigastric pain or burning may enable clinicians to optimally tailor treatment. Surprisingly, GNOM encodes an ARF guanine-nucleotide exchange factor (ARF-GEF) that regulates the formation of vesicles in membrane trafficking. In 10 centers in the Netherlands, patients admitted to the hospital or visiting the outpatient clinic with a recent TIA or ischemic stroke were prospectively and consecutively enrolled between October 2002 and May 2003. On the fifth day of her hospital stay, she underwent an exercise test, where no ischaemic response occurred.

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Of the components of the Child-Pugh and MELD systems, albumin level is the most useful predictor of survival. A large number of oral cancer patients shows poor or partial response to chemotherapy and the mechanisms are poorly understood. We maintain that more consistency is needed in evaluating and treating neutropenia among ELBW neonates. Immunohistochemistry of human malignant astrocytoma cells xenografted to rat brain: apolipoprotein E.

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After a stepwise procedure, the only DR alleles significantly associated with the disease were DR3 (very strongly, protection) and DR4 (weakly, protection). Detailed histochemical analysis of coronary thrombi obtained freshly from acute phase of myocardial infarction patients may provide information necessary to understand the mechanism of coronary occlusive thrombus formation.

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Establishment of an enzyme-linked immunosorbent assay for measurement of sotalol. Higher radiant exposure resulted in larger ablation volume (mass) which increased the recoil momentum. Analysis of the results of several important recent studies has led to a set of tentative ideas concerning the oligomerization of proteins and peptides.

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The blood and lymphatic stream and the mucociliary pathways are demonstrated on the medial maxillary sinus wall to study the influence on wound geometry. Ultraviolet exposure alters human immunity by many means, including affecting circulating T-cells. The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer.

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Normally, the epithelium has a tremendous capacity to repair itself following injury. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

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The voltage-gated sodium channel is the primary target site of pyrethroids, which constitute a major class of insecticides used worldwide. However, anti-SPACA7 did not inhibit fertilization of cumulus-free eggs. In group II, a 0.6-mm diameter fiber was implanted in the same manner.

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The electronics of the CZT are modified so as to obtain a faster response. The possible factors of infection, biochemical parameters, and the efficiency of antiviral therapy were assessed. High initial dose therapy does not enhance virologic response, compared to standard combination regimen. Utilizing prior biological knowledge to restrict the set of candidate SNP pairs to be tested can alleviate this problem, but systematic studies that investigate the relative merits of integrating different biological frameworks and GWAS data have not been conducted. The objective of this randomized, double-blind, placebo-controlled study was to evaluate the efficacy and tolerability of the zolmitriptan conventional tablet at three different doses for the treatment of a single migraine attack in adolescents.

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Disseminated Aspergillosis Following Treatment with Corticosteroids in a Patient with Autoimmune Hemolytic Anemia. All patients, immobilized in a customized head mask integrated into a stereotactic system, were planned on an inverse treatment planning system using 5 or 7 coplanar, equidistant beams and 5 intensity steps. Case 2 and 3 are alive at present, 21 and 5 months postoperatively, respectively.

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Ultrathin cryosections of placenta were used for detection of the distribution of antigens by immunofluorescence and subsequently by immunoelectron microscopy of the same ultrathin cryosection. While evidence for the functional organization of human premotor cortex accumulates, much less is known about the underlying anatomical properties of this brain region. The current study evaluated the efficacy of radiation and concomitant high-dose superselective intra-arterial cisplatin infusion (RADPLAT) for patients with advanced hypopharyngeal cancer.

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Liver dysfunction and liver disease had never been pointed out in his medical history. Patients receiving sibenadet therapy three times daily exhibited statistically significantly greater improvements in BCSS total score than those receiving placebo or bronchodilator therapy alone.

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The higher order moments of the relative particle velocities reveal strong evidence for a qualitative difference between two distinct regimes which are nevertheless connected by a smooth crossover. Intensive collaborative interventions improve depression outcomes, but the benefit of less intensive interventions is not clear. We balance the spectrum uniformity with interpixel cross talk and vignette and then allow the designer to select optimal structure values of the defocusing spectroholographic storage system, i.e., the defocusing value, aperture size, and fill factors for the spatial light modulator and CCD.

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First, we present a likelihood approach to estimate parameters of a discrete-time Markov model. Within the N-terminal region of the Pbx homeodomain, we have identified a residue that is required for cooperative DNA binding with three Hox gene products but not for cooperativity with Engrailed-2 (En-2). Deep body temperatures not higher than approximately 37.9 degrees C and not less than 36.4 degrees C (accompanied by hand temperatures of not less than 19 degrees C) do not negatively affect rifle marksmanship performance, even if significant respective sensations of heat and cold are present.

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Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity. A novel insight into neuroprotection against hypoxic/ischemic stress.

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Patients with longer duration of the illness had less improvement on positive symptoms with risperidone treatment. Plasma HVA in adults with mental retardation and stereotyped behavior: biochemical evidence for a dopamine deficiency model.

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The HGN has an excitatory effect on the internal anal sphincter, and the PuN on the external anal sphincter. A lectin-EIA for agalactosyl IgG is a novel biomarker for IBD, especially in patients with CD.

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In this review, we discuss alpha-proteobacterial genome evolution and highlight strategies and mechanisms used by these bacteria to infect and multiply in eukaryotic cells. Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis. The Wellcome Tropical Research Laboratories in Khartoum (1903-1934): an experiment in development.

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Our results also have important implications for the long-term management of these patients and strategies for containing costs over the life course of the patient. The defect of peroxisomal enzymes was already present 18 days before the onset of the disease. DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly. The nonpainful/painful sensations, pressure, cross-sectional area, wall tension, and strain were evaluated.

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Administrative coverage data are commonly used to assess coverage of mass vaccination campaigns. Variables which might predict the response to salvage radiotherapy in chinese patients with biochemical uniplex drug testing failure after radical prostatectomy. Using this procedure for daunorubicin coupling to monoclonal anti-CEA we found no significant polymerization of the conjugate and a full recovery of the pharmacological activity as tested in vitro on CEA producing human colon adenocarcinoma cells.

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