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Soviclor (Acyclovir)

Soviclor is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Soviclor is converted to an active form by the virus itself, and the virus then uses the active form of Soviclor rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Soviclor into new viral DNA stops the production of the DNA. Virally infected cells absorb more Soviclor than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Soviclor in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Better understanding the mechanisms of leptin resistance should facilitate therapeutic approaches to reverse the phenomenon of selective leptin resistance. These studies support a functional role for endogenous endothelin as a potentially pathophysiological vasoconstrictor peptide hormone in the regulation of cardiovascular, renal, and endocrine function. We have examined the effect of amino acid substitution(s) in this region on T7 phage growth and on the interaction of the polymerase with thioredoxin. Molecular characterization of well-differentiated human thyroid carcinomas by cDNA arrays. With the use of a structured interview schedule, in-home interviews were conducted by a Hmong or a Cambodian bilingual staff person with the adult having primary responsibility for family meal preparation.

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The transfer of molecules between cells during cognate immune cell interactions has been reported, and recently a novel mechanism of transfer of proteins and genetic material such as small RNA between T cells and antigen-presenting cells (APCs) has been described, involving exchange of extracellular vesicles (EVs) during the formation of the immunological synapse (IS). Thin-section chest CT findings in polymyalgia rheumatica: a comparison between with and without rheumatoid arthritis.

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The problems and possibilities inherent in attempting to couple these components into a generic model of productivity are discussed. To describe a family pedigree with a previously undescribed association of autosomal dominantly inherited ocular abnormalities. Effects of a long-term spaceflight on immunoglobulin heavy chains of the urodele amphibian Pleurodeles waltl. These results suggest that colonoscopy should be the method of choice in colon cancer screening. The present systematic review involved studies conducted in recent years to analyze the knowledge, attitudes and behavior of Malaysian healthcare providers regarding breast cancer, in attempts to obtain an overall picture of how well equipped our healthcare providers are to provide optimal breast cancer education, and to see their perceptions and actual involvement in said education.

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Calcium-dependent nonspecific permeability of the inner mitochondrial membrane is not induced in mitochondria of the yeast Endomyces magnusii. Malnutrition in patients with CP is not just a complication of this disease, but has an important impact on its course. These analyses should preferably consider multiple perspectives and allow for the fact that the majority of the benefits accrue in the long-term future. We propose that in cases where this minimum plasma phenylalanine level is not reached, plasma tetrahydrobiopterin should be measured or alternatively other symptomatic family members should be screened. To eradicate Helicobacter pylori before the occurrence of precancerous changes is important to prevent gastric carcinogenesis.

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A prospective study of the roles, responsibilities and stresses of chaplains working within a hospice. A further series of experiments is necessary to elucidate the pathophysiological role of leptin in the differentiation of gastric adenocarcinoma. Superior labrum, anterior-posterior lesions and biceps injuries: diagnostic and treatment considerations. The dynamics of a periodically delta-kicked Hamiltonian system moving at low speed (i.e., at speed much less than the speed of light) is studied numerically.

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The rDFC induced by SV40Tag gene could be cultured and passaged in vitro, which retained the stable proliferation and differentiation characteristics and could be used for periodontal tissue engineering research. The mortality attributable to smoking and alcohol consumption decreased in the city of Barcelona during the study period. The characteristics of eosinophilic ureteritis and idiopathic segmental ureteritis are sufficiently overlapping and so uncommonly reported as to raise a nosological issue.

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Human superoxide dismutase A of the common phenotype SOD A1 is present in two electrophoretic forms in erythrocytes. Prevalence of substance abuse among regular degree health science students in Sheba University College in Mekelle Town, Tigray - Ethiopia. After acid activation of the samples, TGF-beta activity was found in the supernatants of all three mammalian ciliary epithelial cells. Forty human permanent molars with occlusal caries in dentin were selected, embedded in polyester resin, and ground until the carious dentin was exposed.

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Ionizing radiation and doxorubicin both produce oxidative damage and double-strand breaks in DNA. Thermally activated flux avalanches in single crystals of high-Tc superconductors. It is proposed that PsbS controls the macro-organisation of the grana membrane, providing an explanation of its role in NPQ. Flow cytometry analysis showed that PL increased the populations of both apoptotic sub-G1 and G2/M phase.

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After in vivo NE treatment, the expression of the mRNA of the transcriptional factor of IL-6, C/EBP-beta, was elevated earlier (after 45 min of NE infusion) than IL-6 mRNA (after 4 h) and was seen in MCs and NMCs. Besides the Bcl-2 proteins, the mitochondrial organelle contributes to and possibly regulates MOMP, because mitochondrial resident proteins and membrane lipids are prominently involved in the process. Nasal polyposis (NP) in adult population is a common problem in otorhinolaryngology outpatient practice. Information provided by angiogenic factor levels seems to be independent of and is possibly complementary to that provided by conventional serum markers. The discussion reviews the condition of polyarteritis nodosa and analyses the diagnostic difficulties in this case.

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No studies have addressed the spatial complexity of Anopheles arabiensis populations in Zambia or the effects of drought on the genetic structure of this species. Screening for retinopathy of prematurity: does one size fit all?

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Early identification of true responders to acid suppression in functional dyspepsia patients with symptoms of epigastric pain or burning may enable clinicians to optimally tailor treatment. Surprisingly, GNOM encodes an ARF guanine-nucleotide exchange factor (ARF-GEF) that regulates the formation of vesicles in membrane trafficking. In 10 centers in the Netherlands, patients admitted to the hospital or visiting the outpatient clinic with a recent TIA or ischemic stroke were prospectively and consecutively enrolled between October 2002 and May 2003. On the fifth day of her hospital stay, she underwent an exercise test, where no ischaemic response occurred.

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Of the components of the Child-Pugh and MELD systems, albumin level is the most useful predictor of survival. A large number of oral cancer patients shows poor or partial response to chemotherapy and the mechanisms are poorly understood. We maintain that more consistency is needed in evaluating and treating neutropenia among ELBW neonates. Immunohistochemistry of human malignant astrocytoma cells xenografted to rat brain: apolipoprotein E.

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After a stepwise procedure, the only DR alleles significantly associated with the disease were DR3 (very strongly, protection) and DR4 (weakly, protection). Detailed histochemical analysis of coronary thrombi obtained freshly from acute phase of myocardial infarction patients may provide information necessary to understand the mechanism of coronary occlusive thrombus formation.

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Establishment of an enzyme-linked immunosorbent assay for measurement of sotalol. Higher radiant exposure resulted in larger ablation volume (mass) which increased the recoil momentum. Analysis of the results of several important recent studies has led to a set of tentative ideas concerning the oligomerization of proteins and peptides.

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The blood and lymphatic stream and the mucociliary pathways are demonstrated on the medial maxillary sinus wall to study the influence on wound geometry. Ultraviolet exposure alters human immunity by many means, including affecting circulating T-cells. The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer.

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Californiomyces and Typhulochaeta, four species from Nothofagus, species of sect. Relevance was determined considering the therapeutic class, focus on drug shortages, and manuscript type. Extending the dosing interval of an antimicrobial agent that has a PAE has several potential advantages, among them reduced cost, less toxicity, and better compliance among outpatients receiving antimicrobial therapy.

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Normally, the epithelium has a tremendous capacity to repair itself following injury. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

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The voltage-gated sodium channel is the primary target site of pyrethroids, which constitute a major class of insecticides used worldwide. However, anti-SPACA7 did not inhibit fertilization of cumulus-free eggs. In group II, a 0.6-mm diameter fiber was implanted in the same manner.

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Phosphorylation of the carboxy-terminal repeat domain in RNA polymerase II by cyclin-dependent kinases is sufficient to inhibit transcription. The aborted erection by sympathetic trunks stimulation was partially antagonized by phentolamine. Therefore, it is important to study how lipids influence the functions of the tissue.

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The electronics of the CZT are modified so as to obtain a faster response. The possible factors of infection, biochemical parameters, and the efficiency of antiviral therapy were assessed. High initial dose therapy does not enhance virologic response, compared to standard combination regimen. Utilizing prior biological knowledge to restrict the set of candidate SNP pairs to be tested can alleviate this problem, but systematic studies that investigate the relative merits of integrating different biological frameworks and GWAS data have not been conducted. The objective of this randomized, double-blind, placebo-controlled study was to evaluate the efficacy and tolerability of the zolmitriptan conventional tablet at three different doses for the treatment of a single migraine attack in adolescents.

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The surgical procedure was converted to a laparotomy and abdominal hysterectomy in two patients because of poor visualization during robotic-assisted surgery. Development of treatments with predictive biomarkers requires major changes in the standard paradigms for the design and analysis of clinical trials. Ambulatory laparoscopic cholecystectomy is a safe and effective procedure. Assaying tetanus antitoxin antibody levels on samples of dried blood on filter paper discs in tropical countries. Changes in energy conservation and electron transport associated with NADH dehydrogenase.

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Our results demonstrate that elevated doses of ethanol induce HSP in various brain areas, namely, cerebellum, hippocampus, and to a lesser extent, striatum or liver. Nursing interventions to reduce exposure are critical and need further study. RpoS is a key factor for acid stress management in many enterobacteria.

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The present study presents experiments on ATP-Pi exchange and phosphorylation of the calcium-transport-ATPase of sarcoplasmic reticulum vesicles by orthophosphate under conditions of ATP-Pi exchange, as well as on Ca-independent and Ca-dependent phosphorylation in the absence of ATP, ADP and calcium outside. The most recent example being the 2009 pandemic H1N1 virus which codes for only 11 amino-acids of the C-terminus.

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Disseminated Aspergillosis Following Treatment with Corticosteroids in a Patient with Autoimmune Hemolytic Anemia. All patients, immobilized in a customized head mask integrated into a stereotactic system, were planned on an inverse treatment planning system using 5 or 7 coplanar, equidistant beams and 5 intensity steps. Case 2 and 3 are alive at present, 21 and 5 months postoperatively, respectively.

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Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity. A novel insight into neuroprotection against hypoxic/ischemic stress.

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Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon. New work is shedding light on the mechanosensitive properties of SFs, including that these structures can respond to mechanical tension by rapid reinforcement and that there are mechanisms to repair strain-induced damage. Association between anal function fluconazole 150 mg 1 dose of prednisone and therapeutic effect after preoperative chemoradiotherapy followed by intersphincteric resection.

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Administrative coverage data are commonly used to assess coverage of mass vaccination campaigns. Variables which might predict the response to salvage radiotherapy in chinese patients with biochemical uniplex drug testing failure after radical prostatectomy. Using this procedure for daunorubicin coupling to monoclonal anti-CEA we found no significant polymerization of the conjugate and a full recovery of the pharmacological activity as tested in vitro on CEA producing human colon adenocarcinoma cells.

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Accumulation and distribution of uranium in rats after chronic exposure by ingestion. Research is ongoing to fully elucidate these biochemical mechanisms, and well-designed clinical trials are planned to investigate the antitumor potential of modern nitrogen-containing bisphosphonates in the clinical setting. Individuals with Prader-Willi syndrome have speech and atomoxetine hcl specification language impairments, suggesting possible involvement of the perisylvian region of the brain. After the procedure, the patient had a reduction in pain and an increase in range of hip motion.