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Specific roles for Notch 1 and 2 on cannabinoid-induced effects were determined by transient transfection of Notch 1 or 2 shRNA vectors before stimulation with AEA or 2-AG. The 8-hr EC 50 values for cadmium, chromium and copper were 0.6, 2.4, and 1.4 mg/L, respectively. The concentration of 6-keto-prostaglandin F1alpha is markedly elevated at the site of blastocyst implantation in the rat.

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Stab wounds are the most common penetrating trauma to the kidney. The data suggest pliability of centromeric chromatin in response to epigenetic triggers, and the non-essential nature of the regions of delayed replication for centromere function. We evaluated the patient for etiology of the fever and adenopathy, which were unresponsive to antibiotic therapy. The absence of these two preferentially phosphorylated oligosaccharides resulted in greatly reduced amounts of the lysosomal form of the enzyme with increased secretion into the medium.

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One hundred and one patients with vertebral artery injuries were included in the study. We used a well-differentiated HCC cell line (HAK-1A) and a poorly differentiated HCC cell line (HAK-1B) established from a single nodule with histological heterogeneity. Increased orotate excretion was found in some of the RS girls and mothers.

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Except for one case, all perforator flaps healed without complications and the functional results were satisfying. Their present distribution and genetic structure were shaped by a series of lake level fluctuations which caused cycles of isolation and admixis and promoted dispersal events. One pair of 11 nucleotide sites in the coding regions of viral structural protein (VP) 2 and VP6 was found to be complementary specifically among Wa-like strains. The best activity was observed with nonsubstituted quinoxaline 1,4-dioxides in positions 6 and 7 of the aromatic ring and with a hydrogen or chloro substituent in para position of the phenyl group.

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The key point of study on CO2 removal by microalgae cultured in a photobioreactor is to improve CO2 removal capability. Thus, despite the capacity of PKC to phosphorylate TPs in HEK 293 cells and the likely activation of PKC by TP stimulation, this enzyme, like protein kinase A, contributes marginally to rapid, agonist-induced phosphorylation of either TP isoform. Propylthiouracil hepatotoxicity mimicking autoimmune chronic active hepatitis in a girl. Results showed that correct answers were increased, in LTM measures, in the subjects that were given the emotional version of the test. Cardiac amyloidosis in hereditary neuropathic amyloidosis diagnosed by endomyocardial biopsy.

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Trends in the numbers of active and discontinued orthodontic treatments in the General Dental Service 1964-1986/87. Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status. Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus. On the causes of lung hyperinflation during bronchoconstriction.

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Light microscopy and SEM generate information on the morphology of foreign matter particles. Is hemofiltration following acute kidney failure in elderly cardiovascular surgery patients justified? Instead of binding RNA, the RBD of Y14 engages its RNP1 and RNP2 motifs to bind Mago. Electromagnetic navigation is a new technique that can be used with bronchoscopy to obtain samples of small peripheral nodular lesions and enlarged mediastinal lymph nodes. Phase-transfer catalytic determination of phenols as methylated derivatives by gas chromatography with flame ionization and mass-selective detection.

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Effects of spiroconjugation on the calculated singlet-triplet energy gap in 2,2-dialkoxycyclopentane-1,3-diyls and on the experimental electronic absorption spectra of singlet 1,3-diphenyl derivatives. Automatic registration using implicit shape representations: applications in intraoperative 3D rotational angiography to preoperative CTA registration.

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These results suggested that arousal level was reduced after high intensity exercise and reached a state near optimal level after medium intensity exercise. Activity in these neurons is associated with radula protraction, which occurs as a component of a number of different feeding movements. Medial preoptic/anterior hypothalamic lesions induce a female-typical profile of sexual partner preference in male ferrets. Establishing the psychiatric liaison nurse role: collaboration with the nurse administrator. It has been shown that pollen as a dietary supplement may increase the establishment of generalist predatory mites, and therefore pest control by these mites can be provided.

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Consistently, this occurs concomitantly with a significant down-regulation of the phosphorylation of the Akt effectors ribosomal S6 protein (S6) and eukaryotic initiation factor 4E binding protein1 (4EBP1) controlling protein synthesis. Since the area of necrosis in this case report coincided with the anatomic distribution of the derivatives of the congenitally reduced or absent dorsalis pedis artery, we suggest that insufficient blood flow to the dorsal and medial sides of the foot, and to the hallux contributed to the necrosis. The authors examined patients with penetrating cerebrocranial trauma (CCT) and uneventful course of traumatic disease (30) and those with CCT complicated by intracranial purulent process (24 persons). Differentiation and activity of mast cells following immunization in cultures of lymph-node cells.

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A retrospective analysis has been made of patients who had been classified (on the basis of measurements of serum thyroxine and thyroid hormone uptake test) as equivocal thyrotoxic (273 patients) or as equivocal hypothyroid (352 patients). Microvascular ACE is unlikely to participate in the pathogenesis or complications of hypertension in this model. In nonretarded autistic, receptive developmental language disordered, and normal subject groups, we recorded in auditory and visual target detection tasks two neurophysiological components of the event-related brain potential, Nc and P3b.

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New substituted 2-(pyrazol-1-yl)-dialkylacetanilides with potential local anesthetic and antiarrhythmic action. Of twenty-eight limbs with tissue loss, twenty-two were salvaged without further reconstructive surgery. Statistical analyses showed good interfilter fibre size correlation for all types of asbestos. Completion of the Frommelt Attitude Toward Care of the Dying Scale, Death Attitude Profile-Revised Scale, and a demographic questionnaire. This review focuses on our current knowledge in the biochemistry and localization of the main cell wall polymers including pectin, hemicellulose, cellulose and callose from several pollen tube species.

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Arthrogryposis multiplex congenita refers to a clinical condition or syndrome characterised by multiple congenital contractures that affect two or more different areas of the body. We also evaluated the antioxidant enzyme superoxide dismutase (SOD) and histology of lung tissue and liver. The exact nature of the decrease in foot skin blood flow seen after a change in posture remains unsettled. Plasmalogens and oxidative stress: evidence against a major role of plasmalogens in protection against the superoxide anion radical. Effect of setback Le Fort I osteotomy on midfacial soft-tissue changes as evaluated by cone-beam computed tomography superimposition for cases of skeletal Class III malocclusion.

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This is the first local reported case in this archipelago, where L. Unfortunately, the standard TEM technique needs complex and rather expensive equipment, demands high skill, and is attended by bleeding and oozing that may be challenging. Our results suggest that adaptive evolution occurred during the period of time following the duplication event (functional divergence) and that a change in the selective pressures arose in class 2 hemoglobin in relation to the acquisition of a symbiotic function. We have previously reported a dramatic prostate enlargement with concurrent chronic hyperprolactinemia and elevated serum androgen levels in a PRL transgenic mouse (Mt-PRL) with ubiquitous expression of the transgene.

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We have developed a computer program, named PDBETA, that performs normal mode analysis (NMA) based on an elastic network model that uses dihedral angles as independent variables. The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106. An in vivo single-center study, performed and analyzed with an assay based on image processing analysis, demonstrated the antiwrinkle activity of a formulation containing the Aframomum angustifolium seed extract. Neurologic recovery according to the spinal fracture patterns by Denis classification. In fact, ribulose-1,5 bisphosphate carboxylase purified from embryos manifested subunit composition similar to that of leaves.

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Previously, we developed an in vitro assay to determine if borreliacidal antibody production could be augmented by treatment with different cytokines. Cooling to the ground state of axial motion for one atom strongly coupled to an optical cavity. This study provides new insight into the cellular and molecular pathogenesis of GIT1-associated neurological diseases. Prominent gastrointestinal symptoms are rare, and small-bowel findings range from severe villous atrophy (SVA) and partial villous atrophy (PVA) to normal mucosa with inflammatory changes. The effective dimerization constants of MB and TB were evaluated in the presence of each bacterial strain at a concentration of 10(8) CFU/ml.

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Human immunodeficiency virus/acquired immune deficiency syndrome: a survey of the knowledge, attitudes, and beliefs of Texas registered nurses in the 21st century. The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicase. Pharmacognostical studies on the root and rhizome of Globba racemosa

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The reasons for geographical maldistribution of South African doctors are discussed. A phase I multiple dose, dose escalation study of cG250 monoclonal antibody in patients with advanced renal cell carcinoma. Galactography also offers the major advantage of precisely locating the topographic location of the mammary lesion, thus enabling the surgeon to adopt an appropriate procedure that removes all diseased tissue and structures as is essential for histological success.

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Expression of the actin binding protein alpha-actinin has been strongly correlated with the invasive phenotype of GBM in vivo. We identified and quantified 88 proteins, including proteins putatively involved in energy metabolism, cell rescue and defense, molecular signaling, and secondary metabolism. Quercetin, 7,8-dihydroxy-4-methyl coumarin, curcumin, resveratrol and vanillin are therefore effective in protection of human single cell DNA from oxidative attack. Differences in the length and area between the right and left sides became progressively larger from the Yayoi to modern periods. The impact of psychosomatic co-morbidity on discordance with respect to reasons for encounter in general practice.

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The numbers of false-positive and false-negative diagnoses of individual lesions were higher (not statistically significant) with dynamic MR images than with unenhanced MR images. The experiments varied in modality (auditory, visual), task demands (comprehension task vs. As an example, we deal with the measured data for complex reflectivity of a KCl crystal and complex nonlinear susceptibility of a polysilane. Life history of Genarchopsis goppo Ozaki, 1925 (Trematoda: Hemiuridae) from the freshwater fish Channa punctata.

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The inhibitor of microtubule polymerization colchicine has a synergistic effect on CD13-mediated aggregation, suggesting an inhibitory role of microtubules in this process. However, the automated TMH and NIKBUT were not in agreement with traditional measurements using fluorescein staining.

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The Anaphase Promoting Complex/Cyclosome (APC/C) in complex with its co-activator Cdc20 is responsible for targeting proteins for ubiquitin-mediated degradation during mitosis. Analyses of mice with targeted deletions in the genes for alpha3 and beta1 integrin suggest that the alpha3beta1 integrin heterodimer likely determines the organization of the extracellular matrix within the basement membrane of skin.

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Ascertainment of photophobia and phonophobia during migraine: preferred close-ended questions. Global warming, ecological disruption and human health: the penny drops. Two methods using a Taylor expansion of the model around the expectation of the random effects or a simulated value, using then Monte Carlo integration, are proposed and compared. These findings are consistent with a model for Rex-mediated trans-activation in which Rex-viral mRNA complexes are targeted for nuclear export by the direct action of the activation domain.

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A thorough understanding of the structural integrity of the linker, the payload and the conjugation site during biological exposure is critical throughout the process of novel linker-payload design and optimization of PK profile. A 4.7-kb insert of pJML1, one of the transformants, was partially sequenced and found to contain the right section of transposon Tn3 from the middle of the TnpR resolvase gene to the right inverted repeat RI(R), including the TEM-1 gene.

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Osteoporotic vertebra and hip fractures are major causes of dysfunction, disability, mortality and impaired life quality in the ageing population. Liquid-crystal-filled polymer structure devices offer a very low cost switchable spatial phase modulator.

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Based on semi-empirical quantum chemical calculations, a multiple linear regression analysis of the various electronic properties with the 29Si chemical shifts has been attempted. The gene for hPD-ECGF was localized to chromosome 22 by analysis of a panel of human-rodent somatic cell hybrid lines. It has been demonstrated that the psychoneurosomatic interrelations are implicated in the occurrence of the main most prevalent cardiovascular diseases in children. The authors performed a retrospective review of data obtained in 11 patients who were treated at a university-based referral practice between July 1988 and September 2001 and who presented with acute facial nerve paralysis mimicking Bell palsy.

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A case-control study of incident rheumatological conditions following acute gastroenteritis during military deployment. A combination of two probes, each labeled with a different fluorochrome, was used successfully to simultaneously identify two cell types in a mixture.

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Potent In Vitro Antiproliferative Synergism of Combinations of Ergosterol Biosynthesis Inhibitors against Leishmania amazonensis. However, large variations in the initial fallout also occurred locally or even on a meter scale. Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi). Quantum entanglement in plasmonic waveguides with near-zero mode indices. elegans Homolog of RBBP6 (RBPL-1) regulates fertility through controlling cell proliferation in the germline and nutrient synthesis in the intestine.

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This paper examined the 12-month rate of mental disorders and subsequent service use among Canadian seniors aged 65-79 and 80 and over and adults aged 20-49 and 50-64. To investigate the effect of active fraction A in Guizhi Decoction (Fr.A) on dual-directional thermoregulation and its mechanism of influencing heat shock protein (HSP) in hypothalamus. Volume estimates were calculated as an ovoid based on the three maximum orthogonal measurements for the haemangioma, and blood velocity was assessed by Colour Flow Mapping, Colour Doppler Energy Imaging, and Spectral Doppler techniques using a Sequoia 512 Acuson scanner. PET/CT was performed before and after treatment, and the ratio of tumor area activity to non-tumor area activity (T/N) was calculated.

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Infants with congenital long QT syndrome (LQTS) and 2:1 atrioventricular block (AVB) have been recognized as a clinical subset of children with LQTS. Here, we present a simple, new model for evaluating energy-supply technologies and their improvement trajectories against climate-change mitigation goals. However, distinguishing LPL from MZL and from atypical cases of CLL can sometimes be difficult because of overlapping features. However, the rate of death from causes other than disease was higher in the surgery group than in the control group. Cold plasma-induced surface modification of heat-polymerized acrylic resin and prevention of early adherence of Candida albicans.

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After comparison of available sequences of sensitive and resistant type I topoisomerases, the aspartic acid at position 221 of vaccinia virus topoisomerase I is mutated to a valine. Chemokines fluctuate in the progression of primary breast cancer.

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The secondary virus and bacterial infections may develop in the patients who were followed-up the long term period. While there is lack of evidence to support the exact duration of treatment, antipsychotics should not be continued chronically for agitation and psychosis related to critical illness. Thus, in addition to targeted effects of damage induced directly in cells by irradiation, a variety of untargeted effects may also make important short-term and long-term contributions to determining overall outcome after radiation exposures.

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Biofeedback aims to give people with continence problems tangible information to help them maximise their control over elimination. The AMPK (AMP-activated protein kinase) is a highly conserved eukaryotic protein serine/threonine kinase.

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Class stability from waves 1 to 2 was moderate, with greatest agreement for the infrequent drinking class. Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot.

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This flow was found to be independent of pH over a wide range (2-12), of the acetonitrile percentage in the electrolyte. Both conditions showed a redundancy gain when compared with displays containing a target and a noise letter. Severity of MDV lesions was nearly identical in all vaccinated groups in both experiments. Maintenance immunosuppression regimens after the first and second grafts were similar, consisting of a combination of a calcineurin inhibitor, mycophenolate mofetil, and prednisone.

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Of special interest is the elaboration of the petal into a nectar spur, a major innovation for the genus. Oral ftorafur plus intramuscular thiotepa as adjuvant chemotherapy in patients with breast cancer.