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These results show that medial temporal hypoperfusion can be detected in degenerative dementias by SPECT. Tyrosine hydroxylase (TH) immunostaining of dopaminergic neurons of the substantia nigra was performed in a subset of animals. However, MT and its mRNA levels increased markedly when the Hepa-1c1c7 cells were cultured with the OA-treated conditioned media from the RAW 264.7 cells.

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A randomised, open-label, single dose, four-period crossover study was performed in healthy male human subjects to compare the pharmacokinetics of formoterol fumarate (CAS 43229-80-7) after inhalation from two different hydrofluoroalkane (HFA) pressurised metered dose inhaler (pMDI) formulations at two dose levels, 12 and 24 microg. With few exceptions, dental global budgeting did not improve the distribution of dental care and dentist supply. It is unlikely that the promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human PI 3-kinase have a major impact on insulin secretion, insulin sensitivity, or the risk of type 2 diabetes in Finnish subjects.

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The effect of hypoxia on permeability and bacterial translocation in Caco-2 adult and I-407 fetal enterocyte cell culture models. Secreted aspartyl peptidases (Saps) are virulence attributes produced by Candida albicans that participate in multiple aspects of the fungal biology and pathogenesis. A quantitative model of error accumulation during PCR amplification. Clinical significance is a decision based on the practical value or relevance of a particular treatment, and this may or may not involve statistical significance as an initial criterion.

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Photocatalytic degradation of 2-phenethyl-2-chloroethyl sulfide in liquid and gas phases. The variables predictive of drug use for one or both racial groups were limited to sociodemographic characteristics and preincarceration behaviors such as age at release, prior commitments, and preincarceration employment.

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Mathematical modeling of fetal splenic growth: use of the Rossavik growth model. The surgical solution is always individual and respects the specificity which need not be symmetric on both extremities. A 20-yr-old female college basketball player suffered from a 7-month history of debilitating low back and left leg pain. The effects of medication on mortality, weight gain, serology, lesions and reisolation of M gallisepticum 21 days following infection were studied. We have sought to better define the role of WT1 in this process by identifying downstream targets of WT1 during normal gonadal development.

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To estimate the effectiveness of the influenza vaccine under different criteria for selecting patients for swabbing. Erectile dysfunction: prevalence and relationship to depression, alcohol abuse and panic disorder. The inhibition potency was quantified (i.e., cyclosporin A IC50 approximately 7 microM), revealing incongruent relative sensitivities among the substrate markers, with H2FDA generally the most sensitive of the series of substrate markers evaluated.

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Using nonlinear mixed effects modeling with pooled data from 383 healthy volunteers, 181 patients with metastatic RCC, and 26 patients with other solid tumors in 17 trials, the disposition of axitinib was best described by a 2-compartment model with first-order absorption and a lag time, with estimated mean systemic clearance (CL) of 14.6 L/h and central volume of distribution (V(c)) of 47.3 L. Characterization of endothelial cell locomotion using a Markov chain model.

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Weak monoclonal antibodies were used as ligands in a high-performance liquid affinity chromatography system. By adjusting the reaction conditions and purification procedure, it was possible to isolate hGH derivatives containing up to seven PEG moieties that altered the Stokes radius and thereby the effective molecular masses of the unmodified hormone from 22 to 300 kDa. GSH-C4 and I-152 may be used as Th1 immunomodulators in some pathologies and in ageing where GSH depletion may contribute to the Th1/Th2 imbalance, and in new immunization strategies. Our goal was to define the frequency of asymptomatic herpes simplex virus type 2 shedding by culture and polymerase chain reaction and to correlate our findings with cervical anti-herpes simplex virus type 2 immunoglobulin A production.

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Hemoglobin A1c (HbA1c) is a biomarker used for population-level screening of type 2 diabetes (T2D) and risk stratification. This has led to the formulation of a new hypothesis as to the cause of these disorders. The expression is specific for the metastatic cell line as the closely related, non-metastatic mouse adenocarcinoma cell line CSML-0 does not express Ly-6E.1. 3) Comparison of average ages at death, including death by war, indicated that physical education majors lived 8.572 and 7.792 years less than humanities and science course majors, respectively.

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Cushing syndrome from topical foam steroid use in an adolescent male. The SFJ diameter was categorised as normal, dilated or varicose. The prevalence and functional impact of musculoskeletal conditions amongst clients of a primary health care facility in an under-resourced area of Cape Town. Seventeen females and eight males exposed during gestation to synthetic progestins showed a significantly higher potential for physical aggression than their sex-matched unexposed siblings.

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The findings suggest a lower magnesium requirement for healthy men and women than estimated previously. Activation of both second-messenger pathways produced a time- and dose-dependent increase in the total PA activity. The VortX coil fiducial marker showed a statistically significant increase in retention rate compared with gold seeds or two-band fiducials.

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The correctly implemented exact test leads to results that are similar to those from the homozygosity test proposed by Watterson (1977) for relatively small sample sizes but can still differ substantially for larger sample sizes. To provide an overview of scientifically based smoking cessation interventions for delivery to all tobacco-dependent users. Use of disposable equipment at municipal hospitals and related problems - survey based on questionnaires sent by the Municipal Hospital Association Plasma levels of total glutathione were reduced in SS compared with SR rats, regardless of the level of dietary salt intake.

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One 5 mg tablet of OH was dissolved in distilled water and the solution was instilled into the bladder through the catheter, which has been used for urodynamics and which was then removed. Predictions for impurity-induced Tc suppression in the high-temperature superconductors. Indirect mechanism of histamine-induced nociception in temporomandibular joint of rats. A histopathological and ultrastructural study of eccrine porocarcinoma with special reference to its subtypes.

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Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter. There are essentially two alternative mechanisms for the binding of telomerase to telomeres, assuming that a protective component is initially bound to the telomerase binding region on the telomeres.

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In this study we investigated the lung injury, inflammation, proliferation, and survival signaling responses after repetitive exposure to particulate chromate. Radiocaesium accumulation in stemwood: integrated approach at the scale of forest stands for contaminated Scots pine in Belarus. Activation of vitamin D receptor promotes VEGF and CuZn-SOD expression in endothelial cells.

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A 3 month old infant developed typical symptoms of an acute epiglottitis after feeding him hot vegetables. The effect of these types of treatment were compared in experimental huts on wild populations of Anopheles gambiae Giles and the nuisance mosquito Culex quinquefasciatus Say, both of which are multi-resistant. We then show that a model that uses only expected duration for coordination, rather than kinematic or dynamic variables, can describe the kinematics of interaction of hand transport and preshape under a variety of circumstances, including perturbations of object position and object size. Evaluation of eco-toxicological effects of the parasiticide moxidectin in comparison to ivermectin in 11 species of dung flies. Behavior of mouse spermatogonial stem-like cells on an electrospun nanofibrillar matrix.

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Treating coronary artery disease in diabetic patients with balloons and stainless steel: what is the role of percutaneous coronary intervention? Female offspring that share these antigens with their mate experience reduced fetal wasting, establishing a role for vertical transmission of non-genetic information in reproductive fitness. Warfarin is difficult to administer with the proportion of time achieving therapeutic international normalized ratios varying within and among individuals. Why some interventions are more effective than others is not clear.

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To (1) compare hay fever and asthma-like symptoms in organic and conventional farmers and (2) assess associations between current and childhood farm exposures and respiratory health effects by conducting a survey. Vertically Free-Standing Ordered Pb(Zr0.52Ti0.48)O3 Nanocup Arrays by Template-Assisted Ion Beam Etching. A review of the literature has shown that the objectively measured level of fitness and self-reported physical activity both have a prognostic relationship with death from all causes, independently of BMI. We report on the structural features (eg, Congo red staining, circular dichroism spectroscopy, transmission electron microscopy, and rheometry assays) and osteogenic ability of d-RADA16-RGD peptide hydrogels (with or without basic fibroblast growth factor) due to the better stability of peptide bonds formed by these peptides compared with those formed by l-form peptides, and use them to fill the femoral condyle defect of Sprague Dawley rat model.

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The replicon of pBM02 is of the wide-host range type, and functions in both Gram-positive and Gram-negative bacteria, including Lactobacillus casei, Lactobacillus plantarum, Bacillus subtilis, and Escherichia coli. Effect of ascorbic acid on milk lead and cadmium level on subclinical and clinical cases of mastitis. Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases. Analysis of the location and breadth of these peaks determines the resonator eigenvalues.

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Mean RDI of another tributary - Gufu River and the main river were 70.85 and 68.45 respectively, and the unhealthiest tributary was Gaolan River (with mean RDI of 65.64). The egg samples were then assayed for their cholecalciferol content, and some samples, also for the presence of 25-hydroxycholecalciferol by an HPLC method. RPCH did not initiate the swimmeret rhythm in preparations that showed intermittent or no bursting activity. The biofilms are resistant to a range of antifungal agents currently in clinical use, including amphotericin B and fluconazole, and there appear to be multiple resistance mechanisms. However, the portal venous obliteration may be responsible for the occurrence of sustained portal hypertension and several of the pathological changes in these livers.

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Following the patient journey to improve medicines management and reduce errors. Quantitative agreement between torsion constants obtained from the present FPA studies and previous topoisomer distribution measurements on circular DNAs containing 205 to 217 bp removes a long-standing apparent discrepancy between those two methods. Costs of treatment and costs of hospitalization for gastrointestinal events were also considered.

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Fertility is not affected in rats after 24 hours of testicular torsion and orchiectomy, although there is germ cell injury and a decrease in the percent of haploid cells. To describe the procreative experiences and the attitudes related to paternity held by a sample of incarcerated adolescent males. The role of apolipoprotein A5 in obesity and the metabolic syndrome. The total mAs from the CT examination should be kept as low as possible. The decrease in PGM activity in Kuras was confirmed by measuring the enzyme activity from potato tuber extracts.

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Administration of ghrelin during reperfusion reduced myocardial release of lactate dehydrogenase and myoglobin, indicating protection against cardiomyocyte injury. Antimicrobial Susceptibility Profiles of Staphylococcus aureus Isolates Recovered from Humans, Environmental Surfaces, and Companion Animals in Households of Children with Community-Onset Methicillin-Resistant S. The REH theory of protein and nucleic acid divergence: a retrospective update. The use of thoracic epidural anesthesia and analgesia may reduce the incidence of postoperative renal failure.

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Broad spectrum of applications makes LassoProt a useful tool for biologists, biophysicists, chemists, polymer physicists and mathematicians. After administration of 40 mg of metandienone four bis-hydroxy-metabolites--6 beta,12-dihydroxy-metandienone (IX), 6 beta,16 beta-dihydroxy-metandienone (X), 6 beta,16 alpha-dihydroxy-metandienone (XI) and 6 beta,16 beta-dihydroxy-17-epimetandienone (XII)--were detected in the unconjugated fraction.

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Utility as a rationale for choosing observer performance assessment paradigms for detection tasks in medical imaging. The shape of the action potential in hedgehog ventricular cells at 35 degrees C was similar to that in the rat showing a fast repolarization phase. Authors show the advantages from the correctly conducted educational process and the world experiences in realization of preventive programmes.

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Addition of 1,2-diamino-2-methylpropane gave the corresponding 5,5-dimethyl-3-oxo-1,4-piperazine-2-acetic acid ester. Benign joint hypermobility syndrome (BJHS) is a hereditable disorder of connective tissue, which is characterized by the occurrence of multiple musculoskeletal problems in hypermobile individuals who do not have a systemic rheumatological disease.

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A 69-year-old man underwent an emergency operation for the rupture of descending aorta. The greatest challenge to structural biologists in the post-genomic era is to decipher both stable and transient interactions of protein complexes. A ganglion cyst on the posterior cruciate ligament is an uncommon diagnosis and the clinical manifestations are variable and non-specific.

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The amplification of the amelogenin gene showed the presence of a 977-bp band that belongs to the short arm of chromosome X in all patients but the absence of a 780-bp band of the short arm of chromosome Y in three 46,XX males and in all the 46,XX TH. Many parasite populations are difficult to sample because they are not uniformly distributed between several host species and are often not easily collected from the living host, thereby limiting sample size and possibly distorting the representation of the population. Relationship between practice counselling and referral to outpatient psychiatry and clinical psychology. Yeast and flies with defects in activities that modify the state of chromatin also have abnormal telomere function, but the putative role of chromatin-modifying activities in regulating telomeres in mammals is unknown.

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The aims of this study were to assess orofacial manifestations of disease in patients attending the Bombay Leprosy Project clinics and develop clinical guidelines for dentists. Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. Nitric oxide-releasing poly(vinyl alcohol) film for increasing dermal vasodilation. However, vinculin and CLD4 expression was inversely correlated in neuroendocrine tumors, respectively.

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Immunocytochemical detection of bcl-2 and p53 proteins in B-chronic lymphocytic leukemia patients. This effect could be a partial explanation of the possible clinical improvement brought on by biotin in uremic neuropathy. Sutures are tightened at the free proximal tendon ends to obtain a sufficient strength to traction. In this study, we investigated the mechanism by which selenate exhibits insulin-mimetic properties in two different insulin responsive cell types, primary rat hepatocytes and 3T3 L1 adipocytes.

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Experimental evidence shows that depletion of GOLPH3 abolishes transformation and proliferation of tumor cells in GOLPH3-overexpressing cell lines. Although the cause of the wing phenotype is not determined herein, it likely is caused by the other inversion breakpoint interfering with a different function. Combined pre- and postnatal environmental enrichment programs the HPA axis differentially in male and female rats.

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On-demand clinic: unfinishable consultations, lack of time and clinical problems. Therefore, it is suggested that such crossover responses will contribute to the ipsi- and contralaterally recorded ABR waveform when an ABR recording is carried out without contralateral masking.