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Specifically, biocompatible naphthalene-terminated PEG (NP) and anticancer drugs (curcumin or doxorubicin (DOX)) were simultaneously integrated onto oxidized graphene (GO), leading to self-assembled, nanosized complexes. Analysis of the nucleus-ball preparation by immunofluorescence and electron microscopy demonstrate that the ball contains actin and that intermediate filaments are located between the ball and the nucleus. hydroalcoholic extract administration (CHE, 0.5 and 1.0 g/kg body wt., daily for 7 days) on arterial blood pressure and renal sodium excretion in conscious rats.

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A multivariate logistic regression model indicated that the presence of diabetes mellitus or POAD or both at baseline, decreased postexercise ankle-brachial index, increased arm systolic blood pressure, and current smoking were independently associated with progression of POAD. Patients with Acute, Non-Traumatic Abdominal Pain in German Emergency Departments: A Prospective Monocentric Observation Study

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This adaptability, however, also led to abnormal positioning of the prosthetic radial head with supination, subluxing over the trochlea lateral margin. Defining the transmurality of a chronic myocardial infarction by ultrasonic strain-rate imaging: implications for identifying intramural viability: an experimental study. The sequence length variations of DXS6799, DXS8378, DXS101, HPRTB, and DXS6789 loci on X-chromosome in 98 unrelated Ewenke individuals were investigated. in natural breeding sites in western Venezuela, an area of refractory malaria. Maximizing early treatment with biologics in patients with rheumatoid arthritis: the ultimate breakthrough in joints preservation.

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To compare the influence of underlying airway inflammation and lung hyperinflation on dyspnea during induced bronchoconstriction in subjects with mild asthma (or asymptomatic airway hyperresponsiveness (AAHR). All EC patients who underwent esophagectomy between 1993 and 2010 were included and followed for clinical evidence of recurrent EC. This report is based on qualitative data gathered through a series of focus group discussions with people living with HIV or AIDS and nurses in five African countries.

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Marijuana testing in urine: use of a hexadeuterated internal standard for extended linearity, and ion trap vs mass selective detector gas chromatograph/mass spectrometer systems. Skin and soft tissue infections (SSTIs) caused by Achromobacter xylosoxidans are very infrequent. Neighborhood socioeconomic disadvantage and mortality after stroke.

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With the growing realization that even mild head injury can lead to various types of neurocognitive deficits, medical imaging of brain injury has assumed even greater importance than previously. Thus, it is possible to easily prepare a diverse array of substituted heterocyclic compounds in good yield.

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A case of a swallowed foreign body migrating from the pharynx into the soft tissues of the neck is presented, whose management was complicated by its undetected migration to the superior mediastinum occurring between radiological localization in the neck three days prior to exploration and its attempted removal. It is of paramount importance that we investigate and develop preconditioning-mimetic drugs which may enable an increased tolerance to effort angina, limit infarction size in susceptible patients, and decrease the incidence of sudden cardiac death as a result of ventricular tachyarrhythmias. Social inequalities in the city of Rio de Janeiro: a comparison of the 1991 and 1996 censuses Effects of repeated boluses of sucrose on proliferation and on AOM-induced aberrant crypt foci in rat colon. The tissues were also evaluated for the hydroxyproline content as well as histopathologically.

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Although no extensive homologies were identified, the sequence contained the Gly-X-Ser-X-Gly motif found in prokaryotic and eukaryotic lipases, suggesting a similar activity for the encoded protein. ROS generation and the levels of known antioxidant enzyme genes were assayed.

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A first generation production process based on the cultivation of Escherichia coli in a chemically defined medium, employing a fed-batch strategy, delivered reasonable volumetric productivities (500-750 mg/L) and proved to perform very well across a wide range of E. The steroids and human placental lactogen fell very rapidly but pregnancy specific beta1 glycoprotein declined much more slowly. Surgical margins were pathologically negative in each of the 9 specimens.

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Long-stay patients (1 year or more) saw their doctors for an average of less than 1 hour a year. Che-1/AATF, a multivalent adaptor connecting transcriptional regulation, checkpoint control, and apoptosis. Biomedical research: in universities or in independent or affiliated research institutes? Functionally the significance of the muscular hydrostat model lies in the concept that alterations in organ shape are achieved via muscle contraction driven redistribution of hydrostatic tissue pressure.

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The autonomic changes also included pupillary dilation, increases in arterial pressure and heart rate, and vasoconstriction in renal and mesenteric vascular beds. Motion perception of short-wavelength sensitive cones in glaucoma using random dots moving. This study investigated the effects of AET on QoL and exercise capacity in Nigerians on treatment for essential hypertension. Several differentially expressed genes identified from the microarray results were verified by fluorescence real-time PCR (FQ-PCR) and immunohistochemistry (IHC). The objectives of the present study were to estimate costs of patients and to evaluate the performance of various regression models.

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We suggest that this inner feature arises from a domain of FliG. Despite this, pediatric echocardiographic nomograms are limited and heterogeneous, particularly for neonates and infants. Results indicated that the autistic group was relatively deficient on each of the social competence measures and on one of the role-taking measures. Mechanism studies showed that EKA/B blocked the antinociception of EM-1 by activating neurokinin-1 receptor (NK(1)), whose specific antagonist, SR140333B could fully block EKA/B-induced attenuation on the analgesic response of EM-1.

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Though evidence exists indicating that utricular function is severely if not completely compromised in these animals, it is not yet known whether afferent synapses exist within utricular hair cells of otoconia-deficient mutants. Locked plate fixation of osteoporotic humeral shaft fractures: are two locking screws per segment enough? The results of the cytometric method correlated well with the results of the classic microbiological method.

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Combining visceral and somatic stimuli resulted in distinct elevation of visceral thresholds demonstrating somatosensory masking of the visceral stimulus. The United Nations Relief and Works Agency for Palestine refugees in the Near East (UNRWA) has periodically estimated infant mortality rates among Palestine refugees in Gaza.

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Data were obtained by using prospective electromyographic perineometry measurements to objectively determine perineal muscle function before and after delivery in 102 women. Fomepizole (Antizol) was recently approved by the US Food and Drug Administration for treatment of methanol poisoning. Adjuvant radiation of 60 Gy was given with three-dimensional CT-based planning. Previous studies have shown that Bgp functions as an intercellular adhesion molecule and a canalicular bile salt transporter.

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The prevalence of mediotrusion interferences decreased in some types of malocclusions whilst in others there was no change. The composition of the gas in one patient was analyzed by gas chromatography, which revealed an overwhelming preponderance of nitrogen. Aside from the difference in the fibrotic pattern, these studies showed no indicators of RAGE having an effect on the severity of pulmonary fibrosis following silica injury. Evaluation of low back pain should include tests for degenerative retrolisthesis, especially in patients experiencing radiating sensations with no evidence of root impingement, because abnormal electromyographic findings showing denervation of the paraspinal muscles was most common in patients with degenerative retrolisthesis.

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Finally, strict attention should be paid to the body condition of geriatric horses so as to evaluate adequacy of the ration and the general health of the horse. In this study, we carried out a loss-of-function analysis of myosin thick filaments via gene-specific knockdown or using a myosin ATPase inhibitor BTS (N-benzyl-p-toluene sulphonamide) in zebrafish embryos. PaeX, a second pectin acetylesterase of Erwinia chrysanthemi 3937.

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Twelve had a normal eosinophil count at presentation and 11 had negative serology, although two had neither eosinophilia nor positive serology when first seen. Targeted therapy directed at specific molecular alterations is already creating a shift in the treatment of cancer patients.

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As such, this case may represent an example of irreversible change of a malignant process into a benign tumor probably caused by the action of systemic chemotherapy. Following recurrence, the mass showed clear signs of infiltrative growth, including solid bundles of cells, increased polymorphism and round to oval nuclei with coarse chromatin and distinctive nucleoli. Dopamine-induced localized cutaneous vasoconstriction and piloerection.

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Coral reef health and effects of socio-economic factors in Fiji and Cook Islands. Three groups were shown 14-min TV news bulletins that were edited to display either positive-, neutral- or negative-valenced material. Also, the combination of parental rat strains seems to be critical when searching for blood pressure quantitative trait loci. Advanced functionality and contemporary content have been added to meet the increasing requirements for demonstration of lifelong learning and self-assessment as part of the Maintenance of Certification (MOC) process.

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A retrospective analysis of 106 culture-positive typhoid cases admitted in a tertiary care hospital during the years 2005-2008. Understanding the molecular mechanisms of DENV-induced hepatic injury could facilitate the development of alternate chemotherapeutic agents and improved therapies. Maps of cytoarchitectonically defined cortical areas have proven to be a valuable tool for anatomic localization of activated brain regions revealed by functional imaging studies. Because the patient had a long history of paraplegia despite three previous incomplete tumor resections, we chose not to attempt a fourth resection.

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The results showed high efficiency of phytoplankton and pelotherapy in normalization of urodynamics and microcirculation of the bladder mucosa. Collectively, these observations not only suggest a model in which Mcl-1 confers TRAIL resistance by serving as a buffer for Bak, Bim, and Puma, but also identify sorafenib as a potential modulator of TRAIL sensitivity. Point-of-Care Device for Warfarin Monitoring Used in the J-ROCKET AF Study. The intervention successfully changed student health behaviors on many accounts.

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A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner. Four neoplasms arose on the lower extremities and one case each on the forearm, the lateral aspect of the neck and the penis. EEG, steady (DC) potentials, tissue available O2 were measured and metabolic changes were studied. While some studies suggest that QOL returns to baseline levels at 6 to 9 months postoperatively, others report that QOL is still significantly impaired at 6 and 12 months after surgery.

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Norepinephrine and epinephrine increased the vascular resistance of the umbilical veins in a dose-dependent manner. The emission of the major compound, (Z)-3-nonen-1-ol, is stress-sensitive, and coincides with sexual maturity and crowding. HBA at 5 mg/kg and piracetam at 100 mg/kg could counteract the p-chloroamphetamine-induced deficit. Inpatient resource use and costs associated with switching from oral antipsychotics to aripiprazole once-monthly for the treatment of schizophrenia.

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SOD2 mRNA level was decreased and SOD2 immunoreactive protein and activity remained low. Careful attention is necessary when examining the post-radiation therapy patients. However, this variation is limited to the choice between surgery and radiation rather than to the choice between curative and noncurative treatment.

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Relationships between neurocognitive measures and avoidant symptoms were analyzed using linear mixed models. One hundred and eighty-five mothers, from the maternity wards of University Hospital of Oulu, Finland, completed a self-rating depression scale, the Edinburgh Postnatal Depression Scale (EPDS) twice: first at hospital 2-7 days after delivery and the second time at home 4 months after the delivery. Interestingly, soluble CD44 released by oncostatin M-treated cells retained the ligand-binding properties of the membrane-anchored receptor.

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The kinetics of DNA hybridization have been analyzed by a cooled CCD camera to provide quantitative data. To determine the pattern of inheritance of the disease in a family with 83 members spanning three generations. Thus, ISFETs are suitable for the construction of inexpensive and hence disposable multichannel pH monitoring assemblies of small diameter.

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The respective data form a basis to determine effects of therapeutic approaches, progression of diseases, or technical applications like automated segmentation algorithms applied to different populations. To our knowledge, human pulmonary dirofilariasis has previously not been reported in Arkansas. Both thiazide diuretics and amiloride may reduce the polyuria, but the use of each is associated with problems. We show that we can successfully cope with these effects and that the algorithm is suited for an MCAO system for the future generation of extremely large telescopes.

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Overall, females had higher stress-induced CORT compared to males. This bound indicates that the accuracy of the SVM classifier in the compressed domain is close to that of the best classifier in the data domain. The result show that serum activity of angiotensin converting enzyme was significantly increased in rats after the period of dehydration. Diagnosis was based upon a combination of imaging evidence for thoracic aorta aneurysm and evidence for an infective aetiology including a culture of a causative pathogen, or a favourable outcome with anti-infective therapy.