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Expression of antiapoptotic and proapoptotic molecules in diabetic retinas. To identify gene expression patterns that characterize advanced stage serous ovarian cancers by using microarray expression analysis. Fifteen patients were determined to have PIOS after radiation of NPC.

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Moreover, only a minor proportion of pancreatic cancer patients die from hepatic failure as a direct result of liver metastasis. Citizen groups, though celebrated during their sudden arrival on the lobbying scene, are vastly outnumbered by groups representing elite, occupationally based interests. We give conditions on potential and protocol under which the fluctuations of the dissipative work satisfy an exact symmetry for all times.

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Furthermore, the up-regulation of VGF was confirmed by immunohistochemistry in a subset of melanotrophs. Religiosity and perceived rewards of black and white caregivers.

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Two cases of isolation of Listeria monocytogenes type 1 from vaginal mucus of two pregnant women who underwent premature deliveries with death of foetuses are described. It was considered necessary to maintain 30 degrees flexion of the cubital joint and supination of the antebrachium and use a 35 x 43 cm film to facilitate upper extremity venous system interpretation. The availability of spirometry is an important factor for correctly diagnosing COPD. Bayesian updating was used to predict the performance of each cow in the herd and economic decisions were based on the prediction. YZD is an effective drug in treating CHS, its mechanism might be probably related to the improvement of the memory and the enhancement of DA receptor in cerebral tissue.

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Matrix protein 1 (M1) and nonstructural protein 2/nuclear export protein (NS2/NEP) work in the nuclear export of vRNP by associating with it. T-cell subsets and lymphocyte proliferation in recurrent oral ulcers Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells. The threshold pressure (TP) for tremor and for convulsion was significantly lower in GEPR than in SD rats. Of special interest is that hydrolysis of sphingomyelin to ceramide can modulate dynamics of membrane rafts, which serve as signaling platforms for various receptors.

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Histiocytic medullary reticulosis complicating chronic lymphocytic leukaemia: malignant or reactive? Erythema chronicum migrans and lyme arthritis: field study of ticks. FISH technology using yeast artificial chromosomes (YACs) was employed to determine breakage points, microdeletions and inversions on the affected chromosome.

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To assess whether pain in the anterior-lateral part of the thigh in women affected by endometriosis is due to femoral nerve invasion by endometriotic implants. This may be best achieved through combining earlier mitral valve surgery with the accurate detection and liberal correction of accompanying tricuspid incompetence at the time of initial surgery.(ABSTRACT TRUNCATED AT 250 WORDS) Unanesthetized mice of each sex underwent continuous cystometry before and after administration of atropine (1 mg/kg).

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Treatment of Childhood T-Cell Lymphoblastic Lymphoma-Long-Term Results of the SFOP LMT96 Trial. The results of the study identified that this method was sensitive in detecting weekly changes in early motor recovery. Explicit pre-training instruction does not improve implicit perceptual-motor sequence learning. Discriminant function analysis revealed that snake habitats were characterized by higher shrub cover, whereas successful nests were more likely to occur in areas with tall grass and forbs but reduced shrub cover. Anion binding by transferrins: importance of second-shell effects revealed by the crystal structure of oxalate-substituted diferric lactoferrin.

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Instability and abnormal prosthetic insertion seemed to be the primary factors that led to loosening. Expanded modes of tissue plasminogen activator delivery in a comprehensive stroke center increases regional acute stroke interventions. Although for antiestrogens the beneficial effect sought is a reduction in breast cancer mortality, this could be largely eliminated by a small detrimental effect on cardiovascular disease mortality. A number of implantees are likely to be treated with radiosurgery later in life, but very little is known about the effects of radiosurgery on cochlear implants.

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Nicotine had no effect on measurements, which may possibly be important in the relationship between smoking and ulcerative colitis. This paper presents birth defects mortality statistics and preliminary information on the most recent transition between revisions of the classification. For the last 2 1/2 years, supervision groups for general practitioners have been run at Telemark sentralsjukehus. Smoking prevalence for younger nurses was lower than for other nurses, and these nurses were more likely to report themselves as never having smoked.

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The software for creating all the figures appearing in this paper is available as supplementary material. Bronchial lability was characterized by (1) variability in mean daily peak expiratory flow rate and (2) bronchial responsiveness to either carbachol (as assessed by the threshold dose and the slope of the dose-response curve) or salbutamol (as assessed by the threshold dose and maximal response). In addition, alterations of glutamine synthetase activity, which have been reported in the astroglia of animals chronically exposed to low levels of lead, bear further investigation.

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Nutritional evaluation of caseins and whey proteins and their hydrolysates from Protamex. A 4-h UV irradiation also ensures sterility in the case of very resistant microorganisms and in the presence of high microbial charge (10(8) CFU/ml), but a killing rate of 5 or more is already recorded after the first hour of exposition. Our current knowledge of specific barriers that prevent access to HCT is very limited.

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Extinction of phosphoenolpyruvate carboxykinase gene expression is associated with loss of a specific chromatin-binding protein from a far upstream domain. Lac repressor-operator interaction: N-terminal peptide backbone 1H and 15N chemical shifts upon complex formation with DNA. pneumophila activity of macrophages obtained from either susceptible A/J or resistant BDF1 mice to L.

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Each extract was separated into Coomassie blue-stained patterns of up to 350 polypeptides ranging in isoelectric point from pH 4 to 8 and in molecular weight from 10,000 to 200,000. Prenatal exposure to traffic-related air pollution was associated with behavioral development milestone delays of children in a nationally representative sample in Japan.

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Adequate control was achieved only after a 3-fold reduction in steroid dose. Apart from providing an etiologic diagnosis, there are therapeutic implications from in situ demonstration of myocardial enterovirus infection. In the present study we analyzed the expression of apoptosis regulating genes, viz. ABT-737 is a BH3 mimetic small molecule inhibitor that can effectively inhibit the activity of antiapoptotic Bcl-2 family proteins including Bcl2, Bcl-xL and Bcl-w, and further enhances the effect of apoptosis by activating the proapoptotic proteins (t-Bid, Bad, Bim). The Richmond Agitation and Sedation Scale (RASS) and the Confusion Assessment Method for the ICU were used at least twice a day.

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Slant underestimation: a model based on the size of the viewing aperture. These results suggest that various kinds of CTLs with structural and functional diversities may constitute a recognizing network against invading pathogens such as bacteria and virus, and play essential roles in the defence system of shrimp. Communication between older adults and their physicians about urinary incontinence. Overexpression and mutation of p53 in epithelial ovarian cancer. CCL18-mediated down-regulation of miR98 and miR27b promotes breast cancer metastasis.

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Five hundred and fifty six subjects, known to be homosexuals or intravenous drug abusers and seropositive for HIV antibody, were selected on the basis of their clinical state--symptom free, lymphadenopathy syndrome (LAS), AIDS related complex (ARC), and AIDS. Consequently, those who have most contact with soil, the rural poor, are likely to be at greatest risk of infection. Characterization of a functionally expressed stretch-activated BKca channel cloned from chick ventricular myocytes. Biosynthesis and endocytosis of lysosomal enzymes in human colon carcinoma SW 1116 cells: impaired internalization of plasma membrane-associated cation-independent mannose 6-phosphate receptor.

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We describe the NMR structure of HI0719, the first solution structure for a member of this family. Occurrence of Salmonella spp and Cryptosporidium spp in a French coastal watershed: relationship with fecal indicators. Between 1987 and 2002, 47 patients had been treated for panceatic pseudocysts by transmural or transductal drainage EUS-guided drainage of a pancreatic pseudocyst or pancreatc abscess was carried out in 5 cases.

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Neither the epithelial nor the stromal alterations differed significantly in any of the operated eyes at this stage. The concentration of CPM was determined in the skin and serum of five groups. To describe the use of physiotherapy services and alternative therapies by a population of children with moderate to severe cerebral palsy (CP).

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Effective conservation requires clear objectives and prioritizing actions, not places or species. Cognitive function in Stage 5 chronic kidney disease patients on hemodialysis: no adverse effects of lanthanum carbonate compared with standard phosphate-binder therapy. Trypsin from Atlantic cod (Gadus morhua) was previously demonstrated to have efficacy against influenza viruses in vitro and on skin. In each experiment, between 20 (experiments 1 and 2) and 30 (experiment 3) parasite-free yearling calves were selected and allotted to groups of 10/group.

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The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States. We discussed limitations and recommendations for future research in this area. The cesarean section rate was also found to be lower in adolescent pregnancies.

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In the present study, all grafts were protected with a coincident realignment osteotomy when preoperative radiographs suggested that the allograft would be placed under increased load. Cytomorphometric analysis of keratinized round cells in human oral carcinoma. From a temporal dynamic processing point of view, episodic memory can be divided into three critical time periods: short-term episodic memory with a duration of seconds, intermediate-term episodic memory with a duration from minutes to hours, and long-term or remote episodic memory with a duration from days to years. The expression of wt1 and bcl-2 is considered to have a proliferating and survival supporting effect in leukemia blast cells.

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Major effort should be focused on detailed in vitro and in vivo studies of modified CNCs constructs in order to better understand the integration of CNCs in the biological systems. Bioremediation strategies for removal of residual atrazine in the boreal groundwater zone. Molecular cloning and phylogenetic analysis revealed this C4-activating protease to be carp MASP2, indicating that MASP2 arose before the emergence of bony fish. Pulmonary function tests showed a significant improvement in lung volumes, FEV1, PEFR, SGaw, DLCO, and PaO2.

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Whether a combination of these two medicines will increase therapeutic efficacy deserves further clinical investigation. Transition metal complexes are located at the active sites of a number of enzymes involved in intriguing biochemical reactions. Female Wistar rats received low (8 ppm) or control (30 ppm) zinc diets from the beginning of pregnancy to weaning.

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The proportion of families and family members in whom DNA testing could be used to adjust the estimate of risk. Serum samples were obtained during morning hours and IGF-1 was measured by radioimmunoassay. A new approach to analysis of structural properties of biological neural circuits is proposed based on their representation in the form of abstract structures called directed graphs. Nine hospitals in the Southwest Thames Region of London Obstetric Research Collaborative (STORK).

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The start of the measurement was faster with the CSI than with the BIS after switch-on, and measurement was less disturbed by electric cautery with the CSI. A circadian clock-regulated toggle switch explains AtGRP7 and AtGRP8 oscillations in Arabidopsis thaliana. The concentration of ADAMTS13 in normal plasma was approximately 0.5-1 microg/ml. Our study suggests the existence of tautomers, the carboxamide/carbothioamide group may tautomerize, in the solid state or in solution. Cut-out of the HMA screw was significantly greater than with the other implants.

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Spectroscopic studies of dye-surfactant interactions with the co-existence of heavy metal ions for foam fractionation. Aphasia after hemispherectomy in an adult with early onset epilepsy and hemiplegia.

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To report a case of traumatic lumbosacral dislocation treated with open reduction internal fixation and fusion. pylori eradication yielded a significant reduction of iNOS mRNA in the duodenum of DU and in the antrum of GU. Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens.

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Considering synergistic effects between polymorphisms in oxidative stress-related genes may help in determining the risk profile for PD. All residents aged 25 years or more who underwent coronary revascularisation. Neuropsychological outcome, school achievement, and social adjustment in young adulthood (21-28 years of age) were investigated in a prospectively followed group of 17 children born small for gestational age (SGA) and compared with 30 controls born with appropriate weight. One from column A: choosing between CT, positron emission tomography, endoscopic ultrasound with fine-needle aspiration, transbronchial needle aspiration, thoracoscopy, mediastinoscopy, and mediastinotomy for staging lung cancer. Immunologic defect of the alternate pathway-of-complement activation postsplenectomy: a possible relation between splenectomy and infection.

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Considering the substrate specificity and the results of DNA analysis, amidase from R. The pattern of the Fas antigen distribution in oral stratified squamous epithelia was, with some overlapping, characteristic for each disease.

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The peak incidence in men occurred at 30-34 years of age (14.8). Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brain. Monolayer cultures of rat anterior pituitary cells were incubated with aliquots of chromatographic fractions and the inhibition of release of prolactin in vitro was measured by RIA in order to monitor the purification.

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In many vessels, they are an endothelium-derived hyperpolarizing factor (EDHF). With the advent of genome-wide association studies (GWAS), much progress has been made and several genetic loci have been identified to be associated with serum levels of dehydroepiandrosterone sulfate, testosterone and sex hormone-binding globulin. However, recent successes of integrin antagonists in psoriasis, inflammatory bowel disease, and multiple sclerosis demonstrate the tremendous potential of antiadhesion therapy directed at leukocyte integrins.

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Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit. Also, there were lower error rates under static, as compared to dynamic, conditions. Changes in the hemodynamics of the lung and the right ventricle during rest and exertion in 2 groups of patients with chronic broncho-obstructive syndrome of different severity

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Laboratory examination showed a lymphocytosis, mild thrombocytopenia, marked eosinophilia, and high transaminases. Primer extension analysis of the Q318X variants using fluorescent dideoxynucleotides was performed on CYP21A2 gene-specific PCR-amplified DNA samples from controls, patients, potential carriers and prenatal samples. Therefore, recent research in craniofacial genetics searches for mechanisms responsible for correct cell and tissue interactions, not only within a specific structure, but also in the context of supporting structures.

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The diastereoselective synthesis of the 1-beta-methylcarbapenems, (1R,5R,6S)-6-((R)-1-hydroxyethyl)-2-((S)-1-acetimidoylpyrrolidin-3 - ylthio)-1- methyl-1-carbapen-2-em-3-carboxylic acid and sodium (1R,5R,6S)-6-((R)-1-hydroxyethyl)-2-(5-chloro-2-oxobenzoxazolin-3- y l)-1- methyl-1-carbapen-2-em-3-carboxylate has been achieved. MEMS are small, typically micrometer size devices that can be designed to perform the scanning motion required in an SPM system.

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Immunoblotting analysis of p60-src, the product of the viral oncogen v-src related to the tyrosine kinase family failed to produce any significant changes in protein synthesis and activity during dexamethasone-induced inhibition of HETSR cell growth. We conclude that the apparent inhibition of short-term cytotoxicity of AEA toward C6 rat glioma cells in vitro is caused by binding AEA to serum proteins such as albumin. Thus, this factor should be considered when planning and evaluating clinical trials.

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The WHO method ignores uncertainties regarding daily dose, temporal association, start, duration, and end of herbal use, time to onset of the adverse reaction, and course of liver values after herb discontinuation. Skin lesions were observed at the site of application at the top two dose levels for both species and sexes, and consisted of acanthosis, parakeratosis, and hyperkeratosis of the epidermis and sebaceous gland hyperplasia. However, gonadarche (menarche and breast development) and adrenarche (pubic hair) are affected by different environmental factors, which does not support the three phenotypes to be regarded as indicators of a unitary physiological factor.

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Though in the small sample, mean KS concentration in a Labrador Retriever was higher than in Beagles during the first 10 months. Young congenital heart disease patients with an ICD are at risk for growth-related lead distortion.

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Results of measurement of Peak Expiratory Flow Rate PEFR made on 1315 healthy persons ranging in age from 7-67 who attended a Medical Exhibition in the city of Coimbatore is analysed. Causes associated with decreased salivary IgA levels like malnutrition, stress and tobacco could be related to these findings. Vanadium inhibits placental glutathione S-transferase (GST-P) positive foci in 1,2-dimethyl hydrazine induced rat colon carcinogenesis. Combined ventilation/perfusion scintigraphy is an established method for the diagnosis of pulmonary embolism, but the specificity of the method still is not high enough.

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Meteorological influences on the incidence of aneurysmal subarachnoid hemorrhage - a single center study of 511 patients. In addition, no effects on CD62L expression on bovine neutrophils after whole blood incubation with cortisol or dexamethasone were observed. Signal processing using artificial neural network for BOTDA sensor system. The patient underwent complete excision of the retroperitoneal mass along with a rectosigmoid resection of the involved colon with primary reanastomosis.