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Gaudium (Escitalopram)
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Escitalopram

Gaudium is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of major depressive disorder (MDD) and anxiety disorder. This drug exerts a highly selective, potent, and dose-dependent inhibitory effect on the human serotonin transport. By inhibiting the reuptake of serotonin into presynaptic nerve endings, this drug enhances the activity of serotonin in the central nervous system. Gaudium also has allosteric activity. Moreover, the possibility of interacting with other drugs is considered low. This review covers randomized, controlled studies that enrolled adult patients with MDD to evaluate the efficacy of Gaudium based on the Montgomery–Asberg Depression Rating Scale and the Hamilton Depression Rating Scale. The results showed that Gaudium was superior to placebo, and nearly equal or superior to other SSRIs (eg, citalopram, paroxetine, fluoxetine, sertraline) and serotonin-noradrenaline reuptake inhibitors (eg, duloxetine, sustained-release venlafaxine). In addition, with long-term administration, Gaudium has shown a preventive effect on MDD relapse and recurrence. Gaudium also showed favorable tolerability, and associated adverse events were generally mild and temporary. Discontinuation symptoms were milder with Gaudium than with paroxetine. In view of the patient acceptability of Gaudium, based on both a meta-analysis and a pooled analysis, this drug was more favorable than other new antidepressants. The findings indicate that Gaudium achieved high continuity in antidepressant drug therapy.

Other names for this medication:
Escitalopram, Lexapro, Aramix, Celtium, Cipralex, Citoles, Ectiban, Entact, Esertia, Esipram, Esita, Eslorex, Esram, Gaudium, Lexamil, Lextor, Losiram, Losita, Neozentius, Nexcital, Seroplex, Sipralexa, Tiopram,

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Favorable effects of menopausal hormone substitution therapy on risk factors for ischemic heart disease The masking effect of the Ad surface by the polymer elicited evasion of innate adaptive immune responses and the tumor-to-liver ratio of the complex was significantly elevated 1229-fold greater than that of a naked Ad. Results include successes that promote individual and community health in public housing communities in Los Angeles, including public housing preservation, improved maintenance procedures, and increased tenant participation. Small tumor nodules were the most common cause of missed HCCs with all tests. Psychiatry residents in India were satisfied with most areas of supervision even though it is informal and as-usual (i.e.

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Local application to the round window membrane can be used as an effective treatment in the prevention of cisplatin toxicity. Secondary ion and laser ablation mass spectrometry for the quantitative characterization of styrene-butadiene copolymers. Despite problems with empirical replication of this phenomenon, one fruitful avenue of study has emerged from working memory (WM) experiments where a translational method of anxiety induction (risk of shock) has been shown to disrupt spatial and verbal WM performance. We excluded reverse and hemiarthroplasty procedures, patients with a clearly identifiable cause for pain, such as rotator cuff insufficiency or gross component loosening as seen on plain radiographs, and those with culture-positive aspiration.

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Additional residency positions are not likely to be created and funded. Coronary CT angiography showed that microfistulae arising from multiple arteries may have led to myocardial infarction from intracoronary thromboembolism within the dilated left anterior descending (LAD). Assessment of the contraction synergy of the left ventricle during the ejection period These piRNAs have similar sequence length as those of MILI-bound piRNAs.

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To this purpose, MT polypeptides from different organisms, exhibiting different sequence peculiarities, have been analyzed here. Analysis of differential proteins in laryngeal carcinoma cell line Hep-2 with transfection of LCRG1 Reflux episodes detected by impedance in patients on and off esomeprazole: a randomised double-blinded placebo-controlled crossover study.

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A gradual increase was observed in immunoreactive (ir-) inhibin, with maximal levels at the 17th week. SUMO modification attenuates the capacity of FXR to function as a transcriptional activator.

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(2015) investigate protective mechanisms in survivors of type 1 diabetes by using induced pluripotent stem cells as genetic models, uncovering novel interactions between microRNA and the DNA damage checkpoint pathway. Data were normalized for each model by obtaining values relative to the sum of the three values. Compliance with the newly introduced antibiotic policy was studied for a period of six months.

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Intermittent programmed compression of the chronically ischemic limb is associated with arteriogenesis. Common factors in patients with complicated diseases were determined to formulate and test indications for aspiration. Association constants were estimated from double-reciprocal plots of the data. These partnerships will enable pediatricians to contribute in an effort to reduce the burdens of cardiovascular disease to individuals, families, and society. Confidence in the use of these newer devices will increase as surgeons gain wider experience.

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It will greatly accelerate our understanding of the infection of this pathogen and give us more clues to exploit new vaccines and drugs. We describe a slide assay that allows the demonstration of antigens localized in the nucleus from isolated white blood cells as well as from single tumor cells derived from malignant effusions. Use of frozen semen to avoid human immunodeficiency virus type 1 transmission by donor insemination: a cost-effectiveness analysis. At this point, we believe that the greatest potential for the nude mice lies in their use in testing anticancer therapies for human neoplasms without placing the patients at risk. The structural basis for activation of plant immunity by bacterial effector protein AvrPto.

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Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods. Our main objective was to evaluate whether introducing larvivorous fish to anopheline breeding sites impacts Plasmodium parasite transmission. Simple expressions of the nuclear relaxation rate enhancement due to quadrupole nuclei in slowly tumbling molecules. Increased fetal adiposity: a very sensitive marker of abnormal in utero development. It is concluded that supply of energy to the infusion fluid depends on the flow of fluid through the infusion warmer and the capacity of the infusion warmer.

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Molecular phylogeny of Panaspis and Afroablepharus skinks (Squamata: Scincidae) in the savannas of sub-Saharan Africa. Low-energy electrical catheter ablation of sustained ventricular tachycardia originating from the right ventricle. Demonstration of the existence of the semiquinone form of coenzyme Q during electron transport, coupled with recent evidence that hydrogen peroxide (but not molecular oxygen) may act as an oxidant of the semiquinone, suggests that the highly reactive OH. In the human, the region of the aggrecan gene encoding the CS1 domain exhibits size polymorphism, which can result in variation in the degree of chondroitin sulphate substitution of aggrecan in different individuals.

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The inverse light-scattering problem for polymer dispersed liquid crystal film is considered. Nursing actions to ease the anxiety of a patient with prostatic cancer - a study of a patient disturbed by loss of sexual function 200 g) were subjected to a fractionated course of radiation similar to that used in prophylactic brain irradiation for small cell carcinoma of the lung (2000 cGy in 5 fractions over 5 days with 60Co). Five of the seven patients showed a good to excellent improvement of their lesions.

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scan revealed the presence of bilateral temporal lesions from two arterial ischemic accidents that occurred with an interval of twelve years between them. The molecule resides on a crystallographic inversion center and the biphenyl moiety is essentially planar. The model predictions were validated with batch co-culture experiments performed at the optimal conditions. We analysed effects of intracoronary infusion of low concentration of xanthine oxidase (10 mU/ml) in the presence of xanthine (0,5 mM) (X/XO) on bradykinin, other endothelium-dependent and independent vasodilators (acetylcholine, ADP, SNAP), as well as vasoconstrictor responses to angiotensin I and angiotensin II. The Southern hybridization using labelled beta toxin gene probe revealed the presence of positive signals only in beta producing C.

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Rate-related interval stimulation may be useful when applied in drug-resistant junctional and ventricular tachycardias or runs of ventricular extrasystoles as precursors of a tachycardia. Vascular neoplasms characterized by epithelioid endothelial cells consist of several different entities from benignity to high-grade malignancy. RECENT FINDINGS: The ligament-injured joint is at high risk for osteoarthritis.

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This may lead to difficulties in determining the origin of the cancer and to distinguish a synchronous neoplasm from a metastatic cancer in advanced cases. Phenotype-related alteration in expression of natriuretic peptide receptors in aortic smooth muscle cells. 2,4,5-TP possesses the strongest uncoupling properties followed by 2,4,5-T, MCPA and 2,4-D in that order.

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Fifty patients enrolled in the study underwent plane and three dimensional CT scan (PHILIPS-MX 8000). Prevalence and characteristics of chronic pain in the general Norwegian population. Chalcopyrite (CuFeS2), as an earth abundant and nontoxic chalcogenide compound in the I-III-VI2 family, is a promising class of such materials that exhibit unusual electrical, optical, and magnetic properties. Patterns of behavioral characteristics as indicants of recreation preferences: a canonical analysis.

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Urinary Neutrophil Gelatinase-Associated Lipocalin predicts the severity of contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures. Here, we performed an in vivo study to clarify the role of SFN in initiation and progression of lung adenocarcinoma.

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In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis. In addition representativity has to be proven not only for the main cohort but also for the subgroup of responders with which data analysis will be done. The predictive analysis yields the distribution of a new, out-of-sample effect size, which accommodates not only the heterogeneity of the effects but also the imprecision in the parameter estimates. We investigated the expression profiles of miRNAs in the sera of patients to decipher the complicated factors involved in the development of keloid disease. Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings.

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Chest trauma is associated with a significant mortality in Al-Ain City. Little is known about how two polar flagella, one at each cell pole of the so-called amphitrichous bacterium, are coordinated to steer the swimming. Instead, the ethno-behavioral model postulates that culture-bound syndromes consist of culturally specific behavioral repertoires legitimated by culturally sanctioned norms and concepts, but with both behavior and norms acquired in accordance with basic principles of human learning universal to all cultures.

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A 15-year-old, female, formerly obese adolescent was referred to our day care clinic due to self-induced massive weight loss and depressive symptoms. Synthesis of pre-S fragments of hepatitis B virus proteins and their immunogenicity He suffered from nephrotic syndrome associated with leg edema, which was parallel to the exacerbation of hepatitis.

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Temperature-responsive cellulose by ceric(IV) ion-initiated graft copolymerization of N-isopropylacrylamide. Incidence and relevance of acute kidney injury in patients hospitalized with acute coronary syndromes. Zyxin/paxillin proteins may regulate gene transcription by interaction with transcription factors. Efficacy of partial liquid ventilation in improving acute lung injury induced by intratracheal acidified infant formula: determination of optimal dose and positive end-expiratory pressure level. We present an improved ptychographic method that allows for limited stability of the illumination wavefront and thus significantly improve the reconstruction quality without additional prior knowledge.

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In addition, GRO-alpha may serve as a marker of disease activity. During gastrulation in these frogs, convergent extension produces longitudinal tissue growth from latitudinal elongation and migration of aligned constituent cells. To visualize spatial regulation of stimulated secretion within a contact region, we exposed IgE-sensitized rat basophilic leukemia (RBL) mast cells to a surface that was patterned on the microm scale with hapten-containing lipid bilayers to activate cell surface IgE-receptor complexes. To investigate molecular mechanisms of actin-related defense responses, a cultured tobacco ( Nicotiana tabacum L.) BY-2 cell system was devised. Images in normal subjects and nonjaundiced patients showed rapid concentration of tracer by the liver and the passage of the same into the intestine within 15 to 40 minutes, with or without visualization of the gall bladder.

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One-way analysis of variance and chi 2 analysis were then performed to compared the weight status, nutrient intakes, and demographics of the food patterns. MSI and LOH were found in 15 cases (8 MSI and 7 LOH) in sputum and BAL samples. Polypeptide toxin from sea anemone inhibiting proton-sensitive channel ASIC3 The kinetic mechanism of the SufC ATPase: the cleavage step is accelerated by SufB.

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Low-frequency target strength and abundance of shoaling Atlantic herring (Clupea harengus) in the Gulf of Maine during the Ocean Acoustic Waveguide Remote Sensing 2006 Experiment. Bird species were significantly consistent in colour of grit, and grit of different colours varied in prevalence among species, even when analyses were restricted to a sample from a single locality.

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Unfortunately the detectors of a positron emission tomography system do not register only true coincident events. The main issue in the pathogenesis of fulminating meningococcal sepsis is the formation of antigen-antibody immune complexes leading to the involvement of the microcirculatory channel vessels and disseminated intravascular blood coagulation. The search engines PubMed, Embrace and Cochrane were employed to select articles for further study, and the sample thereby selected comprised adult subjects with full permanent dentition, without missing teeth, malformations or previous orthodontic treatment. Magnetic resonance imaging (MRI) demonstrated an irregular-shaped mass with multiple cysts sized 6 x 4 x 6 cm in the temporal lobe, which manifested mixed signal intensity on both the T1 weighted image and the T2 weighted image. Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailability.

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