Buccastem is the maleate salt form of Buccastem, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Buccastem binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Buccastem maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.
Other names for this medication:
Prochlorperazine,
Compazine,
Antinaus,
Buccastem,
Carmetic,
Darbazine,
Dhaperazine,
Emetiral,
Emidoxyn,
Mitil,
Nautisol,
Novamin,
Prochlor,
Proclorperazina,
Procomp,
Promat,
Roumin,
Stemetil,
Stemzine,
Steremal,
Vergon,
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