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Bicusan (Bicalutamide)

Bicusan is an oral medication that is used for treating cancer of the prostate. It belongs to a class of drugs called anti-androgens which includes flutamide (Eulexin) and nilutamide (Nilandron). Androgens (an example of which is testosterone) are hormones that are produced and released by the adrenal glands. They are responsible for supporting (stimulating) tissues that primarily are thought of as male, for example, the male prostate gland. Male traits that also are influenced by androgens include facial and body hair, and small breasts. Anti-androgens prevent the action of androgens by blocking the receptors for androgens on the cells of tissues, for example, the cells of the prostate gland. In addition to normal prostate cells, androgens also have been shown to stimulate the growth of cancer cells within the prostate. Bicusan is thought to prevent the growth of prostate cancer by blocking the effects of androgens on the cancer cells. Bicusan was approved by the FDA in 1995.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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We compared efficacy and impact on the comfort of ibuprofen (7.5 mg/kg per dose), aspirin (10 mg/kg/dose) and paracetamol (10 mg/kg per dose) on children with fever aged 6-24 months in an open, randomised study with three parallel groups. The HPLC method can be applied directly and successfully for dissolution studies. The analysis of the data obtained made it possible to reveal signs characteristic of patients at high risk of pulmonary complications already on the second day postoperatively. Although recently developed specific and sensitive assays of bioactive dimeric inhibin A and B have given new insights into the pituitary-gonadal axis in adult men and during the adult female menstrual cycle, there have been no reports on circulating inhibin A and B during normal human puberty.

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The correlation analysis has established significant correlations between NO metabolites in urine and plasma in the first MI hours and the data on the clinical status, device characteristics of myocardial lesion extention and prognosis of the disease. Various experiments on synthetic, phantom and human brain data have been carried out and promising results with reduced number of atoms have been obtained on diffusion signal reconstruction, thus illustrating the added value of our method over state-of-the-art SHORE and SPF based approaches.

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Should high hTg levels in the absence of iodine uptake be treated? Sexual maturation of boars and growth of swine exposed to extended photoperiod during decreasing natural photoperiod.

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The accumulated PTTG1 impeded mitotic progression in cells expressing PV. If the Bichon Frise had persistent hypercalcemia, we would have evaluated serum concentrations of ionized calcium, parathyroid hormone, and vitamin D to identify an underlying cause. However, the granting of social security benefits to these patients has not received sufficient attention.

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Here, we define mutations in influenza A subtype H5N1 (avian) HA that alter its specificity for SA either by decreasing alpha2,3- or increasing alpha2,6-SA recognition. The strain was kept on cultivating in his laboratory till 1984 and in our thereafter. Its dysregulation has been suggested to be involved in disorders covering the metabolic X syndrome, such as insulin resistance, obesity, type 2 diabetes, and coronary artery disease. The prostheses resulted in improved swallow efficiency, increased duration of tongue contact to the pharyngeal wall, and improved speed of movement of the bolus from the valleculae to the pyriform sinus.

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Do patients with newly diagnosed type 2 diabetes have impaired physical fitness, and energy expenditures? Experimental in vivo generation of intertypic recombinant strains of HSV in the mouse.

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In this study, we investigated the inhibitory effects of N-acetyl cysteine (NAC) on the growth of the human signet ring cell from the gastric-cancer cell line SJ-89 , via the induction of apoptosis and the arrest of DNA synthesis. Granular and agranular sarcoplasmic reticulum (SR) were also in the vicinity of mitochondria. Future research on ECP should focus on using serial measurements and combining it with other markers of asthma which may increase its clinical usefulness.

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Postnatal development of the mouse volatile papilla taste bud cells. The tissue-specific activation of the LPKPP by the viral enhancer was attributed to HNF-1alpha binding to the LPKPP. However, within the dementia workforce there are concerns about inconsistency and variability in both knowledge of dementia and competency in meeting the needs of those affected. During the period, platelet counts ranged between 1 and 3 million/mm3. Armed with mechanistic and rate constant data, the synthetic practitioner can now apply free radical chemistry to the synthesis of many different classes of target molecule with confidence.

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The imprinting status of IGF2 was detected by restriction fragment length polymorphism. Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. Dissertation abstracts and reference lists of articles were checked and researchers were contacted. Improvement of quality of life (QoL) has become a major endpoint in clinical trials of patients with prostate cancer. To find the coherent transmission coefficient, the anomalous diffraction approach, and the approximation of effective refractive indices are used.

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Anisomycin, an antibiotic that specifically inhibits the peptidyl transfer function of eukaryotic ribosomes, has been used to select resistant mutants in Tetrahymena thermophila. Thus, the sensitivity of the cells to UV-A and gamma-ray irradiation was significantly elevated by CAM. Both of the two products could significantly inhibit the growth of various tumor cell lines in vitro with IC(50) values at muM level through apoptotic pathway.

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The ability of the nanotrigger to activate eNOS combined with a low reactivity in unfavourable NADPH sites makes NT a highly promising tool for targeting eNOS in endothelial cells with a laser pulse. STP-A11-mediated processing of p100 to p52 protein requires proteosome-mediated proteolysis because MG132 treatment clearly blocked p52 production in spite of the expression of STP-A11. One large dose (25 microgram/100 g body weight) of T3 given intraperitoneally caused a rapid recovery of the enzyme activity within 24 h either in the presence or absence of the pituitary.

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These findings suggest that longer looking at faces in infants at risk for ASD might reflect early face-processing difficulties and predicts difficulties with recognizing faces later in life. These observations strongly suggest that the 30 C incubation temperature is more reliable in detecting in-vitro resistance of methicillin-resistant strains of Staphylococcus aureus to cephalothin in agar as well as in liquid media. Body mass index (BMI) (kg/m(2)) has a U- or J-shaped relationship with all-cause mortality in Western and East Asian populations.

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Anterior chest wall involvement in patients with pustulosis palmoplantaris. KEY MESSAGE : Auxin responsive promoter DR5 reporter system is functional in Populus to monitor auxin response in tissues including leaves, roots, and stems. Thus, BM-MSC transplantation, in contrast to transplantation of AD-MSC, resulted in better preservation of the LV ability to contract during ischaemia. Therapeutic recommendations are made after reviewing the evidence from the literature for maximizing the efficacy of pain management techniques for oral surgical pain. We have now identified the tyrosine kinase c-Src as a possible pathway between the mediators of inflammation and the gap junction protein connexin43 (Cx43).

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It cannot be too strongly emphasized, however, that this technique takes time and should be entertained only if the anesthesia care provider is able to maintain adequate oxygenation and ventilation until the airway is secured. The Behavior Rating Scales (BRS) from the Bayley Scales of Infant Development (BSID-II) were used to assess behavior. The presidential address from the 25th Educational and Scientific Symposium of the Society of Critical Care Medicine. However, the consequences of such distortions on the ability to detect biological variation in expression have not been explored sufficiently to define the true extent of usability and limitations of such amplification techniques.

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Cephalosporolides H and I, Two Novel Lactones from a Marine-Derived Fungus, Penicillium sp. The study provides an in-depth description of the microbiota of meat and meat processing environments. The influence of the omission of values below LOQ was related to the underlying shape of the concentration-time profile and fraction of omitted observations.

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Balance of proliferation and cell death between thyrocytes and myofibroblasts regulates thyroid fibrosis in granulomatous experimental autoimmune thyroiditis (G-EAT). A patient with a perimesencephalic subarachnoid haemorrhage gradually developed, within the first day, progressively impaired consciousness, small non-reactive pupils, and defective upward gaze. These results suggest that the combination of aspartic acid and glutamic acid may be useful for induction of tumor cell death, and has the potential for clinical use as a cancer therapeutic agent.

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This assay is of great value for monitoring levels of contaminating DNA in purified and in-process biopharmaceuticals. Information about practice distribution of patients with HIV infection and drug users and information about GP experience and confidence was obtained from a survey of individual GPs in 1988. The effect of ALP on the proliferation of 22 different gynecologic malignant tumors in humans was studied in vitro. Low-affinity extracellular protein interactions are critical for cellular recognition processes, but are not generally detected by methods that can be applied in a high-throughput manner. Identifying psychosocial risk among mothers in an Australian private maternity setting: A pilot study.

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Spin alignment in the production of charm and/or bottom vector mesons via heavy quark fragmentation. Superparamagnetic particles as an oral contrast medium in abdominal magnetic resonance imaging. Macrolide showed moderate antibacterial activity against standard strains of oral related bacteria except Fusobacterium nucleatum.

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MiR-141 Inhibits Gastric Cancer Proliferation by Interacting with Long Noncoding RNA MEG3 and Down-Regulating E2F3 Expression. In a conventional PDF incubated at 60 degrees C for 1 day, the 3,4-DGE concentration increased from 14 to a maximum of 49 micromol/L. This stress-induced change is found in all cell lines examined, independent of the activity of the E1.

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Does low reading achievement at school entry cause conduct problems? Spinal cord injury (SCI) often leads to central pain syndrome including hyperalgesia to mechanical stimulation.

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The effect of the pulsatile electromagnetic field in patients suffering from chronic obstructive pulmonary disease and bronchial asthma. A total of 187 patients with dementia and stroke were compared with 507 controls similar in age and ethnic group. This simple decision tree model provides clinicians with a reliable and practical tool. At last, PPARs action of metabolic regulation could have a role on corrective or even preventive strategies against the metabolic adverse events that are commonly observed with some current psychiatric medications, notably antipsychotics. Cytostatic activity of 18 new phosphonic acid derivatives of cycloleucine, aspartic acid and glutamic acid was tested against human KB and mouse L1210s leukemia cell lines in vitro.

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The biomathematical principles, to which reference must be made for the elaboration of the expert systems, necessary in evaluating biological feedback in particular are analyzed. The lamal meaning of names effect of cisapride on gastric motility was determined in vitro (gastroduodenal preparation of the guinea pig) and in vivo (conscious dog).

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Recent evidence indicates that adiponectin may have protective effects against cardiovascular diseases. We compared the safety and efficacy of calcitriol 3 microg g(-1) ointment and calcipotriol 50 microg g(-1) ointment in a multicentre, randomized, investigator-blinded, left-right comparison in mild to moderate chronic plaque psoriasis affecting sensitive areas, defined as being the face, hairline, retroauricular and flexural areas. Destruction of the membranous septum caused marked increase in the tracheal index in this patient. Cellular DNA damage by the antitumor protein macromomycin and its relationship to cell growth inhibition. Ginseng is a well-known herbal medicine that has been apo lansoprazole vs prevacid vs nexium gaining increasingly popularity as a potential chemopreventive agent.

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The extract of the bark, as well as granulosin (1), exhibited lethality in viromed fda registration certificate the brine shrimp test. Regulation of glycosaminoglycan metabolism by bone morphogenetic protein-2 in equine cartilage explant cultures.

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The coefficient of variation was 1.6 percent between the first and second red cell volume determination in 31 of these subjects. Here we propose a mathematical model in which individuals infected with wild-type influenza, if treated, can develop de novo resistance and further spread the resistant pathogen. Spatio-temporal dynamics timolol side effects topical metronidazole of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw.

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The cells were studied in suspension, during isolation by enzymatic digestion and in vivo. There was dose-dependent efficacy and substantial improvement in a larger cohort of patients in a phase II clinical trial. The rodent model of harmaline-induced tremor has been widely used for experimental analysis of tremor. Within serogroup B, better cross-protection against one subgroup was obtained with a pili vaccine over the counter metronidazole pills for men than a whole cell vaccine which correlated with higher pilus antibody titres induced by the former.

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Anaerobic pretreated paper allopurinol tablets picture process water was characterized in terms of readily biodegradable, slowly biodegradable, very slowly biodegradable and inert wastewater fractions under mesophilic and thermophilic conditions. The purpose of this study was to investigate whether the lipoapoptotic effect of FFAs is determined by the degree of saturation and the chain length, and which pathways might be involved. Neurogenic pulmonary edema is an acute life-threatening complication following central nervous system injury.

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